大鼠患血紫质病期间苯丙氨酸和酪氨酸的分布与代谢
Distribution and metabolism of phenylalanine and tyrosine during tualraemia in the rat.
作者信息
Powanda M C, Dinterman R E, Wannemacher R W, Herbrandson G D
出版信息
Biochem J. 1974 Oct;144(1):173-6. doi: 10.1042/bj1440173.
Abstract
Tularaemia in rats causes a doubling of the serum phenylalanine/tyrosine ratio and a more than twofold increase in muscle phenylalanine which cannot be accounted for by decreased hepatic phenylalanine hydroxylase (EC 1.14.16.1) activity, but appear to result from a generalized movement of amino acids from muscle to liver during infection.
摘要
大鼠兔热病会导致血清苯丙氨酸/酪氨酸比值翻倍，肌肉中苯丙氨酸增加两倍多，这不能用肝脏苯丙氨酸羟化酶（EC 1.14.16.1）活性降低来解释，而似乎是感染期间氨基酸从肌肉向肝脏普遍转移的结果。
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