顺二氯二氨铂（II）与异环磷酰胺联合化疗治疗恶性黑色素瘤（作者译）
[Combination chemotherapy with cis-dichloro-diammineplatinum (II) and ifosfamide in malignant melanomas (author's transl)].
作者信息
Balda B R, Jehn U, Klövekorn W, Wohlrab A
出版信息
Klin Wochenschr. 1981 Jul 15;59(14):781-6. doi: 10.1007/BF01724683.
PMID:7196477
Abstract
We report our results on 9 patients with disseminated malignant melanoma, treated with combination of DDP and IF, 3 in addition with VD. In none of them a complete remission was obtained, the median survival was 4.2 months. These disappointing results, in addition to the rather toxic side effects from the chemotherapy, do not present any benefit over less toxic regimens.
摘要
我们报告了9例播散性恶性黑色素瘤患者的治疗结果，这些患者接受了顺铂（DDP）和干扰素（IF）联合治疗，另外3例还接受了长春花碱酰胺（VD）治疗。他们中无一例获得完全缓解，中位生存期为4.2个月。这些令人失望的结果，再加上化疗相当大的毒副作用，与毒性较小的治疗方案相比并无任何优势。
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