不同大鼠组织中I型己糖激酶同工酶的动力学特性差异及其与巯基抑制剂作用的关系
Difference in kinetic properties between hexokinase type I isoenzymes from various rat tissues with reference to the effect of a thiol inhibitor.
作者信息
Kamikashi T, Kizaki H, Murakami K, Ishibashi S
出版信息
Biochem J. 1974 Jan;137(1):139-42. doi: 10.1042/bj1370139.
Abstract
Hexokinase isoenzyme type I was purified from various rat tissues, and was subjected to kinetic studies in the presence or the absence of p-chloromercuribenzenesulphonate. The mode of the inhibition by the thiol inhibitor was different for the type I isoenzymes obtained from different tissues, suggesting that the type I isoenzymes from different tissues were not identical proteins.
摘要
从各种大鼠组织中纯化出己糖激酶同工酶I型，并在有或没有对氯汞苯磺酸盐存在的情况下进行动力学研究。巯基抑制剂对从不同组织获得的I型同工酶的抑制模式不同，这表明来自不同组织的I型同工酶不是相同的蛋白质。
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