Wyler A R, Robbins C A, Dodrill C B
Epilepsia. 1979 Jun;20(3):279-86. doi: 10.1111/j.1528-1157.1979.tb04805.x.
We report the results of 23 severely epileptic patients who were given EEG feedback training. The paradigm reinforced the patients' 18 Hz activity over the scalp approximation of their focus while suppressing temporalis EMG and low frequency EEG activity. In contrast to other studies using EEG feedback, only 43% of patients showed significant changes in seizure occurrence and a lesser number were felt to have benefited clinically. None of our neuropsychological test parameters were helpful in identifying (prospectively or retrospectively) patients most likely to respond to this treatment. Although a few patients were significantly helped by this training, the mechanism for this effect is unclear.
我们报告了23名接受脑电图反馈训练的重度癫痫患者的结果。该范式增强了患者病灶头皮近似区域的18赫兹活动，同时抑制颞肌肌电图和低频脑电图活动。与其他使用脑电图反馈的研究不同，只有43%的患者癫痫发作有显著变化，临床受益的患者更少。我们的神经心理学测试参数均无助于（前瞻性或回顾性地）识别最可能对该治疗有反应的患者。尽管有少数患者通过这种训练得到了显著帮助，但其作用机制尚不清楚。
