霍奇金病患者的淋巴细胞转化及人单核白细胞趋化因子的产生
Lymphocyte transformation and production of a human mononuclear leucocyte chemotactic factor in patients with Hodgkin's disease.
作者信息
Rühl H, Vogt W, Bochert G, Schmidt S, Schaoua H, Moelle R
出版信息
Clin Exp Immunol. 1974 Jul;17(3):407-15.
Abstract
Human peripheral lymphocytes stimulated with phytohaemagglutinin (PHA) produce a factor with chemotactic activity for homologous monocytes. The production of this factor and lymphocyte transformation was investigated in patients with Hodgkin's disease. It has been found that the PHA response as measured by incorporation of [H]thymidine was markedly depressed in patients when compared to the response of normal lymphocytes. In contrast, the production of the chemotactic factor was not significantly depressed in patients with Hodgkin's disease.
摘要
用植物血凝素（PHA）刺激的人外周淋巴细胞会产生一种对同源单核细胞具有趋化活性的因子。对霍奇金病患者的这种因子产生情况和淋巴细胞转化进行了研究。结果发现，与正常淋巴细胞的反应相比，霍奇金病患者中通过[H]胸腺嘧啶核苷掺入法测定的PHA反应明显降低。相比之下，霍奇金病患者趋化因子的产生并未显著降低。
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Lymphocyte transformation and production of a human mononuclear leucocyte chemotactic factor in patients with Hodgkin's disease.霍奇金病患者的淋巴细胞转化及人单核白细胞趋化因子的产生
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West J Med. 1977 Jan;126(1):14-31.
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Mixed lymphocyte culture stimulatory and responding capacity of lymphocytes from patients with lymphoproliferative diseases.淋巴细胞增生性疾病患者淋巴细胞的混合淋巴细胞培养刺激和反应能力。
Clin Exp Immunol. 1975 Jan;19(1):55-65.
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