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致敏淋巴细胞产生的白细胞趋化因子。

Leukotactic factor produced by sensitized lymphocytes.

作者信息

Ward P A, Remold H G, David J R

出版信息

Science. 1969 Mar 7;163(3871):1079-81. doi: 10.1126/science.163.3871.1079.

DOI:10.1126/science.163.3871.1079
PMID:5764874
Abstract

Lymph node lymphocytes obtained from guinea pigs exhibiting delayed hypersensitivity are stimulated in vitro by specific antigen to produce a soluble factor that is chemotactic in vitro for mononuclear macrophages. The material is nondialyzable, relatively heat stable, and elutes from Sephadex G-100 in the fraction containing molecules smaller than immunoglobulins.

摘要

从表现出迟发型超敏反应的豚鼠获得的淋巴结淋巴细胞，在体外被特异性抗原刺激后，产生一种可溶性因子，该因子在体外对单核巨噬细胞具有趋化作用。该物质不能透析，相对耐热，且从Sephadex G - 100上洗脱时，位于含有小于免疫球蛋白分子的级分中。

相似文献

1
Leukotactic factor produced by sensitized lymphocytes.致敏淋巴细胞产生的白细胞趋化因子。
Science. 1969 Mar 7;163(3871):1079-81. doi: 10.1126/science.163.3871.1079.
2
The chemical mediation of delayed hypersensitivity skin reactions. I. Purification of a macrophage-chemotactic factor from bovien gamma-globulin-induced skin reactions in guinea pigs.迟发型超敏反应性皮肤反应的化学介导作用。I. 从豚鼠牛γ球蛋白诱导的皮肤反应中纯化巨噬细胞趋化因子。
Am J Pathol. 1977 May;87(2):359-74.
3
Interaction between 'sensitized lymphocytes' and antigen in vitro. 3. Release of soluble mediators by particulate antigen.“致敏淋巴细胞”与抗原在体外的相互作用。3. 颗粒性抗原释放可溶性介质
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Characterization of guinea pig lymphocyte-derived chemotactic factor for fibroblasts.豚鼠成纤维细胞淋巴细胞源性趋化因子的特性
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The production by antigen-stimulated lymphocytes of a leukotactic factor distinct from migration inhibitory factor.抗原刺激的淋巴细胞产生一种不同于迁移抑制因子的白细胞趋化因子。
Cell Immunol. 1970 Jul;1(2):162-74. doi: 10.1016/0008-8749(70)90003-1.
6
The release of an endogenous pyrogen from guinea pig leukocytes in vitro: a new model for investigating the role of lymphocytes in fevers induced by antigen in hosts with delayed hypersensitivity.豚鼠白细胞在体外释放内源性热原：一种用于研究淋巴细胞在迟发型超敏反应宿主中抗原诱导发热过程中作用的新模型。
J Exp Med. 1977 May 1;145(5):1288-98. doi: 10.1084/jem.145.5.1288.
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Antigen-enhanced glucosamine incorporation by peritoneal macrophages in cell-mediated hypersensitivity. I. Studies on biology and mechanism.细胞介导的超敏反应中腹膜巨噬细胞抗原增强的氨基葡萄糖掺入。I.生物学和机制研究。
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Alterations of macrophage functions by mediators from lymphocytes.淋巴细胞分泌的介质对巨噬细胞功能的影响。
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10
Lymphocyte chemotaxis in inflammation. VII. Isolation and purification of chemotactic factors for T lymphocytes from PPD-induced delayed hypersensitivity skin reaction site in the guinea-pig.炎症中的淋巴细胞趋化作用。VII. 从豚鼠PPD诱导的迟发型超敏反应皮肤部位分离和纯化T淋巴细胞趋化因子。
Immunology. 1984 Feb;51(2):275-85.

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Lymphokine-mediated stimulation of eosinophil migration in the guinea-pig.淋巴因子介导的豚鼠嗜酸性粒细胞迁移刺激作用。
Immunology. 1981 Nov;44(3):481-8.
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Immunology. 1980 Apr;39(4):607-13.
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Platelet factor 4 is chemotactic for neutrophils and monocytes.血小板第4因子对嗜中性粒细胞和单核细胞具有趋化作用。
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