Ward P A, Remold H G, David J R
Science. 1969 Mar 7;163(3871):1079-81. doi: 10.1126/science.163.3871.1079.
Lymph node lymphocytes obtained from guinea pigs exhibiting delayed hypersensitivity are stimulated in vitro by specific antigen to produce a soluble factor that is chemotactic in vitro for mononuclear macrophages. The material is nondialyzable, relatively heat stable, and elutes from Sephadex G-100 in the fraction containing molecules smaller than immunoglobulins.
从表现出迟发型超敏反应的豚鼠获得的淋巴结淋巴细胞,在体外被特异性抗原刺激后,产生一种可溶性因子,该因子在体外对单核巨噬细胞具有趋化作用。该物质不能透析,相对耐热,且从Sephadex G - 100上洗脱时,位于含有小于免疫球蛋白分子的级分中。