Villeneuve J P, Warner H A
Gastroenterology. 1979 Jul;77(1):143-4.
This case of an adult with cimetidine-induced hepatitis is presented. An etiologic role for the drug was strongly suggested when the patient developed transient hepatic dysfunction after two reexposures to cimetidine, which reverted promptly on withdrawal of the drug. The temporal relation between the administration of the drug and the development of hepatic dysfunction suggests that it is a hypersensitivity type of reaction.
本文报告了一例成人西咪替丁诱发肝炎的病例。该患者两次再次接触西咪替丁后出现短暂性肝功能障碍，停药后迅速恢复，强烈提示该药具有病因学作用。药物给药与肝功能障碍发生之间的时间关系表明这是一种超敏反应类型。
