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职业性吸入石棉颗粒人群中的消化系统癌症:一项侧重于剂量反应的文献综述

Digestive system cancer among persons subjected to occupational inhalation of asbestos particles: a literature review with emphasis on dose response.

作者信息

Schneiderman M A

出版信息

Environ Health Perspect. 1974 Dec;9:307-11. doi: 10.1289/ehp.749307.

Abstract

Human data show a dose-response relationship between industrial exposure to asbestos and later development of cancer of the bronchus and lung and of cancer of the digestive tract. The data do not provide much evidence for a threshold or for the existence of a clearly "safe" level of exposure. Good dose-response data, with quantitative estimates of dose are uncommon; however, in all the literature reviewed only one paper did not support the conclusion that increased exposure to inhaled asbestos particles leads to increased digestive system cancer.

摘要

人类数据显示,工业接触石棉与随后支气管和肺癌以及消化道癌症的发生之间存在剂量反应关系。这些数据没有提供太多关于阈值或明显“安全”接触水平存在的证据。有剂量定量估计的良好剂量反应数据并不常见;然而,在所有 reviewed 的文献中,只有一篇论文不支持吸入石棉颗粒接触增加会导致消化系统癌症增加这一结论。

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Type of asbestos and respiratory cancer in the asbestos industry.石棉行业中的石棉类型与呼吸道癌症
Arch Environ Health. 1973 Nov;27(5):312-7. doi: 10.1080/00039896.1973.10666386.

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