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长期黑暗暴露对幼年和成年大鼠视觉阈值的影响。

The effects of prolonged dark exposure on visual thresholds in young and adult rats.

作者信息

Birch D G, Jacobs G H

出版信息

Invest Ophthalmol Vis Sci. 1979 Jul;18(7):752-6.

PMID:447473
Abstract

A comparison of electroretinogram (ERG) thresholds measured on rats reared in continuous darkness and under cyclic lighting conditions shows that by 30 days of age the dark-reared animals have achieved significantly lower thresholds than the animals reared under cyclic illumination. Ten days of continuous dark exposure produces this same increase in sensitivity in adult rats reared in cyclic lighting. These changes in sensitivity appear to reflect structural changes occurring within the rod outer segments.

摘要

对在持续黑暗环境中饲养的大鼠和在周期性光照条件下饲养的大鼠所测得的视网膜电图(ERG)阈值进行比较,结果表明,到30日龄时,黑暗饲养的动物所达到的阈值明显低于在周期性光照下饲养的动物。在周期性光照下饲养的成年大鼠,连续10天暴露于黑暗环境中会产生同样的敏感性增加。这些敏感性变化似乎反映了视杆细胞外段发生的结构变化。

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