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pH 对分散态和聚集态胶原蛋白热稳定性的影响。

Effect of pH on thermal stability of collagen in the dispersed and aggregated states.

作者信息

Russell A E

出版信息

Biochem J. 1974 Apr;139(1):277-80. doi: 10.1042/bj1390277.

DOI:10.1042/bj1390277
PMID:4478066
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1166277/
Abstract

Thermal stabilities of mature insoluble collagen, salt-precipitated fibrils of acid-soluble collagen and acid-soluble collagen in solution were compared as a function of acid pH. Both insoluble and precipitated collagens showed large parallel destabilization with decrease in pH, whereas the intrinsic stability of individual collagen molecules in dilute solution was comparatively unaffected.

摘要

比较了成熟不溶性胶原蛋白、酸溶性胶原蛋白的盐沉淀原纤维以及溶液中酸溶性胶原蛋白在酸性pH值条件下的热稳定性。不溶性胶原蛋白和沉淀胶原蛋白均随着pH值降低呈现出大幅度的平行失稳，而稀溶液中单个胶原蛋白分子的固有稳定性相对不受影响。

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本文引用的文献

1
The effect of ultraviolet irradiation on soluble collagen.紫外线照射对可溶性胶原蛋白的影响。
Biochem J. 1965 Oct;97(1):139-47. doi: 10.1042/bj0970139.
2
The effect of alkalis on collagen.碱对胶原蛋白的作用。
Biochem J. 1948;43(3):365-72. doi: 10.1042/bj0430365.
3
The role of pH, temperature, salt type, and salt concentration on the stability of the crystalline, helical, and randomly coiled forms of collagen.
J Biol Chem. 1967 Apr 10;242(7):1361-9.
4
Effect of pH on the stability of the collagen fold.
Arch Biochem Biophys. 1966 Nov;117(2):466-8. doi: 10.1016/0003-9861(66)90436-x.
5
On the conformational stability of globular proteins. The effects of various electrolytes and nonelectrolytes on the thermal ribonuclease transition.关于球状蛋白质的构象稳定性。各种电解质和非电解质对热核糖核酸酶转变的影响。
J Biol Chem. 1965 Oct;240(10):3909-23.
6
The effects of salts on the stability of the collagen helix under acidic conditions.盐类在酸性条件下对胶原蛋白螺旋稳定性的影响。
Aust J Biol Sci. 1968 Aug;21(4):821-6. doi: 10.1071/bi9680821.
7
Comparison of lyotropic and chromatographic effects of polar organic solvents on collagen and cellulose.
Biochemistry. 1971 Oct 12;10(21):3890-6. doi: 10.1021/bi00797a015.
8
Effect of alcohols and neutral salt on the thermal stability of soluble and precipitated acid-soluble collagen.醇类和中性盐对可溶性和沉淀性酸溶性胶原蛋白热稳定性的影响。
Biochem J. 1973 Feb;131(2):335-42. doi: 10.1042/bj1310335.
9
Effect of pH on the stability of collagen molecule in solution.pH对溶液中胶原蛋白分子稳定性的影响。
J Biochem. 1973 May;73(5):999-1006. doi: 10.1093/oxfordjournals.jbchem.a130184.
10
Differential anion effects on thermal stability of collagen in the dispersed and aggregated states.不同阴离子对分散态和聚集态胶原蛋白热稳定性的影响。
Biochem J. 1974 Mar;137(3):599-602. doi: 10.1042/bj1370599.