Faergemann J
J Invest Dermatol. 1979 Jun;72(6):326-9. doi: 10.1111/1523-1747.ep12531766.
The purpose of this investigation was to produce experimental tinea versicolor in rabbits and humans with Pityrosporum orbiculare. Inoculation with P. orbiculare under plastic occlusion on the glabrous follicle-rich inside of the rabbit ear resulted in a tinea versicolor-like lesion after 1 week in 3 of 4 animals. One week after inoculation with P. orbiculare under plastic occlusion, experimental infections similar to those found clinically in tinea versicolor were seen in 10 of 12 patients with a history of tinea versicolor and in 3 of 6 normal volunteers. It was not possible to produce experimental infections without occlusion. Spontaneous healing usually occurred.
本研究的目的是用圆形糠秕孢子菌在兔和人身上制造实验性花斑癣。在兔耳无毛且毛囊丰富的内侧进行塑料封闭并接种圆形糠秕孢子菌后，4只动物中有3只在1周后出现了类似花斑癣的病变。在有花斑癣病史的12名患者中的10名以及6名正常志愿者中的3名身上，在塑料封闭下接种圆形糠秕孢子菌1周后，观察到了与临床上花斑癣相似的实验性感染。不进行封闭则无法制造实验性感染。通常会自发愈合。
