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人类转移性脑肿瘤中的毛细血管超微结构。

Capillary ultrastructure in human metastatic brain tumors.

作者信息

Long D M

出版信息

J Neurosurg. 1979 Jul;51(1):53-8. doi: 10.3171/jns.1979.51.1.0053.

DOI:10.3171/jns.1979.51.1.0053
PMID:448419
Abstract

The ultrastructural characteristics of blood vessels within 18 metastatic neoplasms of the brain have been studied. The abnormal permeability to protein-bound tracers was found to be related to defective capillary endothelium. Abnormalities include gap functions, fenestrations of membranes, and open normal junctions. The abnormal capillaries had the character of capillaries from current tissue. Endothelium cell abnormalities were not found in surrounding edematous brain.

摘要

对18例脑转移瘤内血管的超微结构特征进行了研究。发现对蛋白结合示踪剂的异常通透性与毛细血管内皮缺陷有关。异常包括间隙功能、膜窗孔和开放的正常连接。异常毛细血管具有来自当前组织的毛细血管特征。在周围水肿的脑组织中未发现内皮细胞异常。

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