Smith R J
J Natl Med Assoc. 1979 May;71(5):441-4.
In the great majority of patients treated with radiation, only transitory injury to the bowel occurs, but in five percent of patients, permanent damage to the small bowel or rectum is seen. Symptoms of radiation enteropathy may begin four to six months after the treatment is completed or may not present until several years later. Most often, the patient presents with abdominal pain, diarrhea, hematochezia, and signs of malnutrition. Others may present, initially, with intestinal obstruction, perforation, or fistulization. It is important to differentiate this clinical syndrome from recurrent cancer by appropriate radiological studies and biopsies.This paper presents four patients who were treated with radiation for invasive carcinoma of the cervix and subsequently developed radiation enteritis. All were treated surgically and are surviving.
在绝大多数接受放疗的患者中,肠道仅出现短暂损伤,但有5%的患者会出现小肠或直肠的永久性损伤。放射性肠炎的症状可能在治疗结束后4至6个月出现,也可能直到数年之后才出现。最常见的情况是,患者表现为腹痛、腹泻、便血和营养不良的体征。其他患者最初可能表现为肠梗阻、穿孔或肠瘘。通过适当的放射学检查和活检将这种临床综合征与复发性癌症区分开来很重要。本文介绍了4例因宫颈癌浸润性癌接受放疗并随后发生放射性肠炎的患者。所有患者均接受了手术治疗,目前均存活。