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[胸外科感染的流行病学]

[Epidemiology of infections on a thoracic surgery service].

作者信息

Laxenaire M C, Borgo J, Hartemann P, Villiaume J M, Borelly J

出版信息

Ann Anesthesiol Fr. 1979;20(6-7):625-31.

PMID:44977
Abstract

The aim of the present work is to discover the origin of the post-operative infections presented by certain patients following surgery for pulmonary exeresis in a surgical unit that deals both with thoracic and general surgical patients (most commonly cancer surgery). A prospective epidaemiological investigation of 54 pulmonary cases was thus undertaken, lasting for a period of 6 months. This consisted in obtaining multiple microbiological specimens from the patient himself, but also from the patient's environment and from the hospital staff (more than 1000 specimens were examined). The study begins at the stage of entry of the patient to the hospital department and follows him through the operation theatre stage and the post-operative period in the intensive care unit. In the intensive care unit the patients will come into contact with other patients who have been admitted urgently. These cases may or may not be of a pulmonary nature. Among the 54 subjects studied, 19 presented with infectious post-operative complications that led to 2 deaths. In 9 cases the infection was due to auto-contamination. It would appear that the environment plays a very small rôle as a factor leading to the development of post-operative infection since very few of the specimens taken were postive and usually the staphylococci were of various different lysotypes and never corresponding to the lysotype of the infective organism. Some predisposing factors to infection were demonstrated: an association with alcoholism and chronic bronchitis, pre-operatory bronchial suppuration, and widespread pulmonary exeresis was found.

摘要

本研究的目的是找出在一个同时处理胸科和普通外科患者(最常见的是癌症手术)的外科病房中,某些接受肺部切除术的患者术后感染的源头。因此,对54例肺部病例进行了为期6个月的前瞻性流行病学调查。这包括从患者本人、患者的环境以及医院工作人员那里获取多个微生物样本(共检查了1000多个样本)。研究从患者入院阶段开始,跟踪其经过手术室阶段以及重症监护病房的术后阶段。在重症监护病房,患者会与其他紧急入院的患者接触。这些病例可能是肺部疾病,也可能不是。在54名研究对象中,19例出现了术后感染并发症,导致2人死亡。9例感染是由于自体污染。似乎环境作为导致术后感染发生的一个因素所起的作用非常小,因为所采集的样本中很少有呈阳性的,而且通常葡萄球菌属于各种不同的溶菌型,从未与感染病原体的溶菌型一致。研究还发现了一些感染的易感因素:与酗酒和慢性支气管炎有关、术前支气管化脓以及广泛的肺部切除术。

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