来自噬菌体fd、fl和φX174 DNA的嘧啶序列。

Pyrimidine sequences from the DNA of bacteriophages fd, fl, and phi X174.

作者信息

Ling V

出版信息

Proc Natl Acad Sci U S A. 1972 Mar;69(3):742-6. doi: 10.1073/pnas.69.3.742.

DOI:10.1073/pnas.69.3.742

PMID:4501589

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC426548/

Abstract

By the use of techniques previously developed to determine the sequence of large, unique pyrimidine oligonucleotides in bacteriophage fd DNA, pyrimidine sequences in the related phage fl and the unrelated phage varphiX174 amber 3 were determined. The DNA of fl contains many pyrimidine sequences completely identical to those in fd, including one sequence of 20 base residues. The large pyrimidine oligonucleotides in varphiX174 DNA are quite different from those in fd, although some homology is observed. There is present in each of the phage DNAs a pyrimidine oligonucleotide rich in thymidine that contains a common sequence of C_T_T_T_T_T_T_T.

摘要

通过使用先前开发的用于确定噬菌体fd DNA中大型独特嘧啶寡核苷酸序列的技术，测定了相关噬菌体fl和不相关噬菌体φX174琥珀3中的嘧啶序列。fl的DNA包含许多与fd中完全相同的嘧啶序列，包括一个20个碱基残基的序列。尽管观察到一些同源性，但φX174 DNA中的大型嘧啶寡核苷酸与fd中的有很大不同。每个噬菌体DNA中都存在一种富含胸苷的嘧啶寡核苷酸，其包含C_T_T_T_T_T_T_T的共同序列。