Barua D, Watanabe Y
J Hyg (Lond). 1972 Mar;70(1):161-9. doi: 10.1017/s0022172400022208.
Yersinia enterocolitica serotype IX has been found to stimulate the production of vibriocidal antibody against Vibrio cholerae, particularly in Inaba serotype, in experimental rabbits and infected man to a significant degree. This activity could be absorbed by both Inaba and Yersinia antigens from anti-yersinia sera, but Yersinia antigen could not absorb vibriocidal activity from the anti-cholera sera, indicating a unilateral relation.Vibrio agglutinating antibody, particularly against Ogawa, in anti-yersinia rabbit or human sera was found to be less liable to non-specific stimulation.V. cholerae, while removing vibriocidal antibody, could not absorb the Yersinia agglutinin from anti-yersinia sera, suggesting that there is a different determinant for these two types of antibody activities.The non-specific production of vibriocidal antibody by Y. enterocolitica type IX indicates the need for caution in the interpretation of the results of vibriocidal tests where such organisms are prevalent.
已发现小肠结肠炎耶尔森氏菌IX型血清型能刺激实验兔和受感染人类产生针对霍乱弧菌的杀弧菌抗体，尤其是针对稻叶血清型的抗体，刺激程度显著。这种活性可被抗耶尔森氏菌血清中的稻叶抗原和耶尔森氏菌抗原吸收，但耶尔森氏菌抗原不能从抗霍乱血清中吸收杀弧菌活性，表明存在单向关系。在抗耶尔森氏菌兔血清或人血清中发现，弧菌凝集抗体，尤其是针对小川血清型的抗体，较不易受到非特异性刺激。霍乱弧菌在去除杀弧菌抗体的同时，不能从抗耶尔森氏菌血清中吸收耶尔森氏菌凝集素，这表明这两种抗体活性存在不同的决定簇。小肠结肠炎耶尔森氏菌IX型血清型非特异性产生杀弧菌抗体表明，在这类细菌普遍存在的情况下，对杀弧菌试验结果的解释需要谨慎。
