Pykett A H, Preston N W
J Hyg (Lond). 1975 Dec;75(3):399-406. doi: 10.1017/s0022172400024463.
The vibriocidal activity of Inaba and Ogawa antisera, from which cross-reacting agglutinin had been absorbed, was specific for Vibrio cholerae strains of the homologous serotype. No vibriocidal action against strains of the heterologous type was detected. The sera appeared to be equally effective in killing organisms of different biotypes (classical, intermediate, and EITor), provided that these were of the homologous serotype (Inaba or Ogawa). However, they had been raised against strains of the classical biotype only; and sera resulting from immunization with other biotypes had not been prepared. The implications of these findings in immunity to cholera are discussed.
已经吸收了交叉反应凝集素的稻叶型和小川型抗血清的杀弧菌活性，对同源血清型的霍乱弧菌菌株具有特异性。未检测到对异源血清型菌株的杀弧菌作用。只要这些菌株属于同源血清型（稻叶型或小川型），这些血清在杀死不同生物型（古典生物型、中间生物型和埃尔托生物型）的生物体方面似乎同样有效。然而，这些血清仅针对古典生物型的菌株制备；尚未制备由其他生物型免疫产生的血清。本文讨论了这些发现对霍乱免疫的意义。
