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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Mori H, Futatsuya R, Ando I, Shimazu H, Koizumi K, Ando A, Hisada K

Radioisotopes. 1979 Feb;28(2):84-8. doi: 10.3769/radioisotopes.28.2_84.

The experimental studies have demonstrated that 99mTc-gluconate reaches a high concentration in the kidneys within 1-2 hours after injection and its concentration in organs adjacent to the kidney is low. 2) The initial images of serial macroautoradiograms visualized the inner medulla as well as the cortex and outex medulla, whereas the delayed images revealed only the outer cortex and outer stripes in the outer medulla. These findings suggest that this renal agent consists of two components and the delayed component deposits in the convoluted and straight segments of proximal tuble. 3) This renal agent visualizes the calyceal system and excretory pathways in the initial study and the renal morphology in the delayed study. Therefore, using this renal agent, it may be possible to evaluate a variety of renal diseases, including obstructive uropathy, space-occupying lesions, congenital deformities, etc,.

实验研究表明，注射后1 - 2小时内，99mTc - 葡萄糖酸盐在肾脏内达到高浓度，而其在肾脏相邻器官中的浓度较低。2) 连续宏观放射自显影片的初始图像显示了肾内髓质以及皮质和外髓质，而延迟图像仅显示了外皮质和外髓质中的外条纹。这些发现表明，这种肾显像剂由两个成分组成，延迟成分沉积在近端小管的曲段和直段。3) 这种肾显像剂在初始研究中显示肾盂系统和排泄途径，在延迟研究中显示肾脏形态。因此，使用这种肾显像剂，有可能评估多种肾脏疾病，包括梗阻性尿路病、占位性病变、先天性畸形等。

Mori H, Futatsuya R, Ando I, Shimazu H, Koizumi K, Ando A, Hisada K

Radioisotopes. 1979 Feb;28(2):84-8. doi: 10.3769/radioisotopes.28.2_84.

The experimental studies have demonstrated that 99mTc-gluconate reaches a high concentration in the kidneys within 1-2 hours after injection and its concentration in organs adjacent to the kidney is low. 2) The initial images of serial macroautoradiograms visualized the inner medulla as well as the cortex and outex medulla, whereas the delayed images revealed only the outer cortex and outer stripes in the outer medulla. These findings suggest that this renal agent consists of two components and the delayed component deposits in the convoluted and straight segments of proximal tuble. 3) This renal agent visualizes the calyceal system and excretory pathways in the initial study and the renal morphology in the delayed study. Therefore, using this renal agent, it may be possible to evaluate a variety of renal diseases, including obstructive uropathy, space-occupying lesions, congenital deformities, etc,.

实验研究表明，注射后1 - 2小时内，99mTc - 葡萄糖酸盐在肾脏内达到高浓度，而其在肾脏相邻器官中的浓度较低。2) 连续宏观放射自显影片的初始图像显示了肾内髓质以及皮质和外髓质，而延迟图像仅显示了外皮质和外髓质中的外条纹。这些发现表明，这种肾显像剂由两个成分组成，延迟成分沉积在近端小管的曲段和直段。3) 这种肾显像剂在初始研究中显示肾盂系统和排泄途径，在延迟研究中显示肾脏形态。因此，使用这种肾显像剂，有可能评估多种肾脏疾病，包括梗阻性尿路病、占位性病变、先天性畸形等。