Kirwan J R, Byron M A, Winfield J, Altman D G, Gumpel J M
Rheumatol Rehabil. 1979 May;18(2):78-84. doi: 10.1093/rheumatology/18.2.78.
In a quest for a objective assessment of synovitis of the knee, the value of circumferential measurements of the knee at two levels has been tested. Measurement 1 cm above the patella was shown to be more precise and to correlate better with the quantity of synovial fluid aspirated than measurement at mid-patellar level. The size of change necessary for statistical significance frequently exceeded the change likely to be found in clinical practice. The precision of measurement is greater in normal than in rheumatoid knees, and can be increased by using the mean of duplicate measurements rather than a single measurement. In clinical trials, the use of one observer throughout will increase the reliance that can be placed on the changes in measurements.
为了客观评估膝关节滑膜炎，已对膝关节两个水平的周径测量值的价值进行了测试。结果显示，在髌骨上方1厘米处进行测量比在髌骨中点水平测量更精确，且与抽出的滑液量相关性更好。具有统计学意义所需的变化幅度常常超过临床实践中可能出现的变化。正常膝关节测量的精度高于类风湿性膝关节，并且通过采用重复测量的平均值而非单次测量可提高精度。在临床试验中，自始至终由一名观察者进行测量将增加对测量值变化的可信度。
