对神经兴奋性进行整体解释的一次尝试。
An attempt at an integral interpretation of nerve excitability.
作者信息
Neumann E, Nachmansohn D, Katchalsky A
出版信息
Proc Natl Acad Sci U S A. 1973 Mar;70(3):727-31. doi: 10.1073/pnas.70.3.727.
Abstract
A qualitatively consistent integral interpretation of biochemical, electrophysiological, and biophysical data on nerve activity is given in terms of a basic excitation unit. This operational term models a dynamically coupled assembly of membrane components accounting for graded and all-or-none responses upon stimulation. The analysis contains a series of suggestions linking controversial interpretations and is aimed at stimulation of experimental studies providing the basis for a quantitative integral theory of nerve excitation.
摘要
从一个基本的兴奋单元出发，对有关神经活动的生化、电生理和生物物理数据进行了定性一致的整体解释。这个操作性术语对膜成分的动态耦合集合进行了建模，解释了刺激时的分级反应和全或无反应。该分析包含了一系列将有争议的解释联系起来的建议，旨在推动实验研究，为神经兴奋的定量整体理论提供基础。
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