神经母细胞瘤细胞表面膜的糖肽
Glycopeptides from surface membranes of neuroblastoma cells.
作者信息
Glick M C, Kimhi Y, Littauer U Z
出版信息
Proc Natl Acad Sci U S A. 1973 Jun;70(6):1682-7. doi: 10.1073/pnas.70.6.1682.
Abstract
Sequential removal of surface glycopeptides was achieved by subjection of mouse neuroblastoma cells to a two-step trypsin treatment under different conditions. The glycopetides released by each trypsinization step were digested by Pronase and examined on columns of Sephadex G-50. Different chromatographic patterns were found for the two digests. Thus, several groups of glycopeptides can be distinguished by the trypsinization procedure. One group is readily removed and appears to be at a more accessible location on the cell surface. Among the four neuroblastoma clones examined, the glycopeptide patterns from axon-forming cells differed from those of axon-minus cells.
摘要
通过在不同条件下对小鼠神经母细胞瘤细胞进行两步胰蛋白酶处理，实现了表面糖肽的顺序去除。每个胰蛋白酶消化步骤释放的糖肽用链霉蛋白酶消化，并在Sephadex G - 50柱上进行检测。两种消化产物呈现出不同的色谱模式。因此，通过胰蛋白酶消化程序可以区分几组糖肽。一组很容易被去除，似乎位于细胞表面更容易接近的位置。在所检测的四个神经母细胞瘤克隆中，形成轴突的细胞的糖肽模式与无轴突细胞的不同。
相似文献
1
Glycopeptides from surface membranes of neuroblastoma cells.神经母细胞瘤细胞表面膜的糖肽
Proc Natl Acad Sci U S A. 1973 Jun;70(6):1682-7. doi: 10.1073/pnas.70.6.1682.
2
Glycoproteins associated with nuclei of cells before and after transformation by a ribonucleic acid virus.核糖核酸病毒转化前后与细胞核相关的糖蛋白。
Biochemistry. 1973 Mar 13;12(6):1221-6. doi: 10.1021/bi00730a032.
3
Fucose-containing glycopeptides from the cell surface of Chinese hamster ovary cells grown in the presence or absence of cyclic AMP.在有或没有环磷酸腺苷存在的情况下培养的中国仓鼠卵巢细胞表面含岩藻糖的糖肽。
Nat New Biol. 1973 Jul 18;244(133):86-9. doi: 10.1038/newbio244086a0.
4
Glycopeptides from the surgace of human neuroblastoma cells.来自人神经母细胞瘤细胞表面的糖肽。
Cancer Res. 1976 Dec;36(12):4520-4.
5
Surface glycoprotein characteristic of the differentiated state of neuroblastoma C-1300 cells.神经母细胞瘤C - 1300细胞分化状态的表面糖蛋白特征。
Exp Cell Res. 1971 Dec;69(2):440-2. doi: 10.1016/0014-4827(71)90247-3.
6
Change in cell-surface glycoproteins of mouse embryos before implantation.着床前小鼠胚胎细胞表面糖蛋白的变化。
Proc Natl Acad Sci U S A. 1973 Jun;70(6):1645-8. doi: 10.1073/pnas.70.6.1645.
7
Membrane glycopeptides from subcellular fractions of control and virus-transformed cells.来自对照细胞和病毒转化细胞亚细胞组分的膜糖肽。
J Biol Chem. 1974 Mar 10;249(5):1541-50.
8
Comparative studies on the carbohydrate-containing membrane components of normal and adenosine 3':5'-cyclic monophosphate-treated Chinese hamster ovary cells.正常及经3':5'-环磷酸腺苷处理的中国仓鼠卵巢细胞含碳水化合物膜成分的比较研究。
Biochem J. 1973 May;134(1):329-39. doi: 10.1042/bj1340329.
9
Surface membrane glycopeptides correlated with tumorigenesis.与肿瘤发生相关的表面膜糖肽。
Biochemistry. 1973 Nov 20;12(24):4864-9. doi: 10.1021/bi00748a009.
10
Surface membrane glycopeptides which coincide with virus transformation and tumorigenesis.与病毒转化和肿瘤发生相关的表面膜糖肽。
J Virol. 1974 May;13(5):967-74. doi: 10.1128/JVI.13.5.967-974.1974.
引用本文的文献
1
SANTAVAC ™: A Novel Universal Antigen Composition for Developing Cancer Vaccines.SANTAVAC™：一种用于开发癌症疫苗的新型通用抗原组合物。
Recent Pat Biotechnol. 2017;11(1):32-41. doi: 10.2174/1872208309666161130140535.
2
Design of universal cancer vaccines using natural tumor vessel-specific antigens (SANTAVAC).利用天然肿瘤血管特异性抗原设计通用型癌症疫苗（SANTAVAC）。
Hum Vaccin Immunother. 2015;11(3):689-98. doi: 10.1080/21645515.2015.1011022.
3
Cellular cancer vaccines: an update on the development of vaccines generated from cell surface antigens.细胞癌症疫苗：细胞表面抗原疫苗开发的最新进展。
J Cancer. 2010 Nov 29;1:230-41. doi: 10.7150/jca.1.230.
4
Effects of ovarian hormones on cell membranes in the rat uterus. III. The surface carbohydrates at the apex of the luminal epithelium.卵巢激素对大鼠子宫细胞膜的影响。III. 腔上皮顶端的表面碳水化合物。
Cell Biophys. 1981 Dec;3(4):305-20. doi: 10.1007/BF02785116.
5
Modulation of cell-surface antigens of a murine neuroblastoma.小鼠神经母细胞瘤细胞表面抗原的调节
Proc Natl Acad Sci U S A. 1974 Jan;71(1):187-91. doi: 10.1073/pnas.71.1.187.
6
Alterations of membrane glycopeptides in human colonic adenocarcinoma.人结肠腺癌中膜糖肽的改变。
Proc Natl Acad Sci U S A. 1974 Dec;71(12):4869-73. doi: 10.1073/pnas.71.12.4869.
7
Investigation of malignancy-related glycopeptides and their release in vitro and in vivo from ascites tumour cells.恶性肿瘤相关糖肽及其在体外和体内从腹水肿瘤细胞释放的研究。
Ir J Med Sci. 1985 Aug;154(8):292-305. doi: 10.1007/BF02937168.
8
Carbohydrate structure in tumor immunity.肿瘤免疫中的碳水化合物结构
Cancer Metastasis Rev. 1985;4(3):221-60. doi: 10.1007/BF00048097.
9
Development and evaluation of an in vitro virus isolation procedure as a replacement for the mouse inoculation test in rabies diagnosis.狂犬病诊断中用于替代小鼠接种试验的体外病毒分离程序的开发与评估。
J Clin Microbiol. 1989 Nov;27(11):2522-8. doi: 10.1128/jcm.27.11.2522-2528.1989.
10
Synthesis and turnover of plasma-membrane proteins and glycoproteins in a neuroblastoma cell line.神经母细胞瘤细胞系中质膜蛋白和糖蛋白的合成与周转
Biochem J. 1976 Jan 15;154(1):57-64. doi: 10.1042/bj1540057.
本文引用的文献
1
EFFECT OF GLYCOSIDASES ON THE FATE OF TRANSFUSED LYMPHOCYTES.糖苷酶对输注淋巴细胞命运的影响。
Proc Natl Acad Sci U S A. 1964 Sep;52(3):750-5. doi: 10.1073/pnas.52.3.750.
2
The role of sialic acid in determining the survival of glycoproteins in the circulation.唾液酸在决定糖蛋白在循环系统中的存活情况方面的作用。
J Biol Chem. 1971 Mar 10;246(5):1461-7.
3
Carbohydrates in cell surfaces.细胞表面的碳水化合物。
Int Rev Cytol. 1970;29:77-125. doi: 10.1016/s0074-7696(08)60033-9.
4
Regulation of acetylcholinesterase in neuroblastoma cells.神经母细胞瘤细胞中乙酰胆碱酯酶的调节
Proc Natl Acad Sci U S A. 1970 Oct;67(2):786-92. doi: 10.1073/pnas.67.2.786.
5
Major human erythrocyte glycoprotein spans the cell membrane.主要的人类红细胞糖蛋白跨越细胞膜。
Nat New Biol. 1971 Jun 23;231(25):229-32. doi: 10.1038/newbio231229a0.
6
Surface glycoprotein characteristic of the differentiated state of neuroblastoma C-1300 cells.神经母细胞瘤C - 1300细胞分化状态的表面糖蛋白特征。
Exp Cell Res. 1971 Dec;69(2):440-2. doi: 10.1016/0014-4827(71)90247-3.
7
Intercellular contact and cell-surface galactosyl transferase activity (cell culture-mouse-radioautography-contact inhibition-cis-and trans-galactosylation).细胞间接触与细胞表面半乳糖基转移酶活性（细胞培养-小鼠-放射自显影-接触抑制-顺式和反式半乳糖基化）
Proc Natl Acad Sci U S A. 1972 Feb;69(2):485-9. doi: 10.1073/pnas.69.2.485.
8
Neurotransmitter synthesis by neuroblastoma clones (neuroblast differentiation-cell culture-choline acetyltransferase-acetylcholinesterase-tyrosine hydroxylase-axons-dendrites).神经母细胞瘤克隆体的神经递质合成（神经母细胞分化 - 细胞培养 - 胆碱乙酰转移酶 - 乙酰胆碱酯酶 - 酪氨酸羟化酶 - 轴突 - 树突）
Proc Natl Acad Sci U S A. 1972 Jan;69(1):258-63. doi: 10.1073/pnas.69.1.258.
9
Proteins exposed on the surface of mammalian membranes.暴露于哺乳动物细胞膜表面的蛋白质。
Biochemistry. 1972 Jul 4;11(14):2616-21. doi: 10.1021/bi00764a011.
10
Effect of growth on the glycoproteins from the surface of control and Rous sarcoma virus transformed hamster cells.生长对正常及劳斯肉瘤病毒转化的仓鼠细胞表面糖蛋白的影响。
Biochemistry. 1971 May 25;10(11):2176-80. doi: 10.1021/bi00787a034.
Zotero 插件