Samuell C T
Urol Res. 1979 Mar 23;7(1):5-12. doi: 10.1007/BF00262919.
Using an electroimmunoassay technique for uromucoid in urine, the excretion of this protein has been studied in normal subjects, calcium stone formers and in patients with chronic renal failure. In the normal subjects there was no significant difference in daily excretion between males and females, but a positive correlation with urine volume was demonstrated for this group. No significant difference in daily uromucoid excretion was found between normal and stone forming subjects. In the presence of chronic renal failure uromucoid excretion was found to be reduced and correlated with overall renal function as assessed by creatinine clearance.
采用免疫电泳技术检测尿液中的尿类黏蛋白，对正常受试者、含钙结石患者以及慢性肾衰竭患者体内该蛋白的排泄情况进行了研究。在正常受试者中，男性和女性的每日排泄量无显著差异，但该组中尿类黏蛋白排泄量与尿量呈正相关。正常受试者与结石患者的每日尿类黏蛋白排泄量无显著差异。在慢性肾衰竭患者中，尿类黏蛋白排泄量减少，且与通过肌酐清除率评估的整体肾功能相关。
