转运RNA生物合成：丝氨酸和脯氨酸转运RNA前体的核苷酸序列
Transfer RNA biosynthesis: the nucleotide sequence of a precursor to serine and proline transfer RNAs.
作者信息
Barrell B G, Seidman J G, Guthrie C, McClain W H
出版信息
Proc Natl Acad Sci U S A. 1974 Feb;71(2):413-6. doi: 10.1073/pnas.71.2.413.
Abstract
The nucleotide sequence of a transfer RNA precursor molecule coded by bacteriophage T4 has been determined. The molecule is a single polynucleotide chain which contains two transfer RNA species that are destined to recognize serine and proline. The 3' -CCA(OH) termini of both mature transfer RNA species are absent in the precursor molecule; these termini must therefore be added enzymatically at a subsequent stage of maturation. Nucleotide residues unique to the precursor are located at both ends of the molecule and between the two transfer RNA sequences.
摘要
噬菌体T4编码的一种转运RNA前体分子的核苷酸序列已被确定。该分子是一条单链多核苷酸链，包含两种注定要识别丝氨酸和脯氨酸的转运RNA。两种成熟转运RNA的3'-CCA(OH)末端在前体分子中不存在；因此这些末端必须在成熟的后续阶段通过酶促添加。前体特有的核苷酸残基位于分子的两端以及两个转运RNA序列之间。
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Nat New Biol. 1973 Nov 7;246(149):6-11. doi: 10.1038/newbio246006a0.
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