• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Interspersion of repetitive and single-copy sequences in nuclear ribonucleic acid of high molecular weight.高分子量核糖核酸中重复序列与单拷贝序列的散布情况。
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1108-12. doi: 10.1073/pnas.71.4.1108.
2
Repetitive and non-repetitive sequence in sea urchin heterogeneous nuclear RNA.海胆不均一核RNA中的重复序列和非重复序列。
J Mol Biol. 1974 May 5;85(1):103-26. doi: 10.1016/0022-2836(74)90132-6.
3
Repetitious and unique sequences in the heterogeneous nuclear and cytoplasmic messenger RNA of mammalian and insect cells.哺乳动物和昆虫细胞的不均一核信使核糖核酸及细胞质信使核糖核酸中的重复序列和独特序列。
Cell. 1974 Sep;3(1):23-30. doi: 10.1016/0092-8674(74)90033-6.
4
Base composition of the rapidly hybridizing sequences of the dRNA fractions.双链RNA组分中快速杂交序列的碱基组成。
Cell Differ. 1972 Jun;1(2):127-31. doi: 10.1016/0045-6039(72)90035-8.
5
Sequence composition of rat nuclear deoxyribonucleic acid and high molecular weight nuclear ribonucleic acid.大鼠细胞核脱氧核糖核酸和高分子量核糖核酸的序列组成
Biochemistry. 1974 Feb 26;13(5):841-8. doi: 10.1021/bi00702a001.
6
Studies on nuclear 4.5 S ribonucleic acid III of Novikoff hepatoma ascites cells.诺维科夫肝癌腹水细胞的细胞核4.5S核糖核酸III的研究
J Biol Chem. 1970 Jul 10;245(13):3416-21.
7
Different sequences for 5S RNA in kidney cells and ovaries of Xenopus laevis.非洲爪蟾肾细胞和卵巢中5S RNA的不同序列。
Nat New Biol. 1973 Jan 3;241(105):7-12. doi: 10.1038/newbio241007a0.
8
Clustering of the DNA sequences complementary to repetitive nuclear RNA of HeLa cells.与海拉细胞重复核RNA互补的DNA序列的聚类
J Mol Biol. 1975 Mar 25;93(1):23-38. doi: 10.1016/0022-2836(75)90357-5.
9
Ribonuclease-stable base sequences specific exclusively for giant dRNA.仅对巨大双链核糖核酸特异的核糖核酸酶稳定碱基序列。
Biochim Biophys Acta. 1972 Apr 12;262(4):568-72. doi: 10.1016/0005-2787(72)90502-3.
10
[Double-helical structure and complementary sequence in nuclear mRNA precursors].[核mRNA前体中的双螺旋结构和互补序列]
Usp Sovrem Biol. 1978 Sep-Oct;86(2):163-76.

引用本文的文献

1
C-value paradox: Genesis in misconception that natural selection follows anthropocentric parameters of 'economy' and 'optimum'.C值悖论：源于一种误解，即自然选择遵循以人类为中心的“经济”和“最优”参数。
BBA Adv. 2023 Oct 13;4:100107. doi: 10.1016/j.bbadva.2023.100107. eCollection 2023.
2
Emerging Roles of Repetitive and Repeat-Containing RNA in Nuclear and Chromatin Organization and Gene Expression.重复及含重复序列的RNA在细胞核与染色质组织及基因表达中的新作用
Front Cell Dev Biol. 2021 Oct 6;9:735527. doi: 10.3389/fcell.2021.735527. eCollection 2021.
3
Identification of Xenopus laevis mRNAs with homology to repetitive sequences.与重复序列具有同源性的非洲爪蟾mRNA的鉴定。
Nucleic Acids Res. 1984 Dec 11;12(23):8899-916. doi: 10.1093/nar/12.23.8899.
4
Cloning of sequences expressed specifically in tumors of rat.大鼠肿瘤中特异性表达序列的克隆。
Proc Natl Acad Sci U S A. 1983 Dec;80(24):7524-7. doi: 10.1073/pnas.80.24.7524.
5
Messenger RNA metabolism of animal cells. Possible involvement of untranslated sequences and mRNA-associated proteins.动物细胞的信使核糖核酸代谢。非翻译序列和信使核糖核酸相关蛋白质的可能作用。
J Cell Biol. 1975 Feb;64(2):269-88. doi: 10.1083/jcb.64.2.269.
6
Distribution and virogenic effects of 5-bromodeoxyuridine in synchronized rat embryo cells.5-溴脱氧尿苷在同步化大鼠胚胎细胞中的分布及病毒生成效应
Proc Natl Acad Sci U S A. 1975 May;72(5):1829-33. doi: 10.1073/pnas.72.5.1829.
7
Molecular biology and biochemistry of differentiation.分化的分子生物学与生物化学
Environ Health Perspect. 1976 Dec;18:47-53. doi: 10.1289/ehp.761847.
8
Interspecific "common" repetitive DNA sequences in salamanders of the genus Plethodon.红背无肺螈属蝾螈的种间“共同”重复DNA序列。
Chromosoma. 1976 Oct 12;58(1):1-31. doi: 10.1007/BF00293437.
9
Purification and characterization of two transcribed repetitive DNA fractions from the pigeon genome.鸽基因组中两个转录重复DNA片段的纯化与特性分析
Chromosoma. 1977 Jun 23;61(4):381-94. doi: 10.1007/BF00288621.
10
Preferential expression of unique sequences adjacent to middle repetitive sequences in mouse cytoplasmic RNA.小鼠细胞质RNA中与中度重复序列相邻的独特序列的优先表达。
Nucleic Acids Res. 1979 Oct 10;7(3):751-64. doi: 10.1093/nar/7.3.751.

本文引用的文献

1
Gene regulation for higher cells: a theory.高等细胞的基因调控：一种理论
Science. 1969 Jul 25;165(3891):349-57. doi: 10.1126/science.165.3891.349.
2
Kinetics of renaturation of DNA.DNA复性动力学
J Mol Biol. 1968 Feb 14;31(3):349-70. doi: 10.1016/0022-2836(68)90414-2.
3
Molecular weights of some HeLa ribosomal RNA's.一些海拉细胞核糖体RNA的分子量
J Mol Biol. 1969 Feb 14;39(3):545-50. doi: 10.1016/0022-2836(69)90144-2.
4
Transcription of nonrepeated DNA in neonatal and fetal mice.新生和胎儿小鼠中非重复DNA的转录
Proc Natl Acad Sci U S A. 1971 Jan;68(1):172-6. doi: 10.1073/pnas.68.1.172.
5
The genes for silk fibroin in Bombyx mori.家蚕中丝心蛋白的基因。
J Mol Biol. 1972 Oct 14;70(3):637-49. doi: 10.1016/0022-2836(72)90563-3.
6
Hybridization properties of DNA sequences directing the synthesis of messenger RNA and heterogeneous nuclear RNA.指导信使核糖核酸和不均一核核糖核酸合成的DNA序列的杂交特性。
J Cell Biol. 1971 Sep;50(3):774-86. doi: 10.1083/jcb.50.3.774.
7
DNA-RNA hybridization in vast DNA excess.在大量DNA过量情况下的DNA-RNA杂交
Nat New Biol. 1971 May 5;231(18):8-12.
8
General interspersion of repetitive with non-repetitive sequence elements in the DNA of Xenopus.非洲爪蟾DNA中重复序列元件与非重复序列元件的总体散布情况。
J Mol Biol. 1973 Jun 15;77(1):1-23. doi: 10.1016/0022-2836(73)90359-8.
9
Preparation, molecular weight, base composition, and secondary structure of giant nuclear ribonucleic acid.巨大核糖核酸的制备、分子量、碱基组成及二级结构
Biochemistry. 1973 Jun 5;12(12):2330-8. doi: 10.1021/bi00736a023.
10
Size and distribution of the repetitive segments of the Drosophila genome.果蝇基因组重复片段的大小与分布。
J Mol Biol. 1972 Feb 28;64(1):211-9. doi: 10.1016/0022-2836(72)90330-0.

高分子量核糖核酸中重复序列与单拷贝序列的散布情况。

Interspersion of repetitive and single-copy sequences in nuclear ribonucleic acid of high molecular weight.

作者信息

Holmes D S, Bonner J

出版信息

Proc Natl Acad Sci U S A. 1974 Apr;71(4):1108-12. doi: 10.1073/pnas.71.4.1108.

DOI:10.1073/pnas.71.4.1108
PMID:4524620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC388172/
Abstract

Nuclear RNA of high molecular weight, approximately 15 to 30 x 10(3) nucleotides long, isolated from rat ascites cells, has been shown previously to contain both middle repetitive and single-copy sequences. However, it was not known whether these sequences were located on separate molecules or whether they were interspersed within the same molecule. The present communication distinguishes between these possibilities and shows that a large proportion of nuclear RNA of high molecular weight consists of interspersed middle repetitive and single-copy sequences.

摘要

从大鼠腹水细胞中分离出的高分子量核RNA，长度约为15至30×10³个核苷酸，先前已证明其含有中度重复序列和单拷贝序列。然而，尚不清楚这些序列是位于不同的分子上，还是散布在同一分子内。本论文区分了这些可能性，并表明大部分高分子量核RNA由散布的中度重复序列和单拷贝序列组成。