Freyler H, Klemen U
Wien Klin Wochenschr. 1979 May 11;91(10):344-8.
1642 diabetics with retinopathy were controlled at half-yearly intervals over 4 to 10 years (6 years on average) using fundus photography, fluoresceinangiography and measurement of visual acuity. 83 of these patients died and the data documented in 43 patients over a mean period of 5.2 years prior to death allowed a retrospective evaluation of the clinical findings and therapeutic results. 27 patients had undergone bilateral and 16 unilateral photocoagulation at the beginning of the observation period. 9 patients were blind already at the outset. Of 13 patients who became blind during the observation period 10 had not undergone photocoagulation of the affected eye. The time span between blindness and death was shorter (1.5 years) in the 3 patients (5 eyes) who had undergone photocoagulation than in the untreated diabetics (4.3 years). All 23 patients in whom the initial visual acuity was maintained had undergone photocoagulation. Presence of florid diabetic retinopathy or nephropathy adversely influenced the results of photocoagulation.
1642例患有视网膜病变的糖尿病患者在4至10年(平均6年)的时间里每隔半年接受一次检查,检查手段包括眼底摄影、荧光素血管造影和视力测量。这些患者中有83人死亡,43例患者在死亡前平均5.2年的时间里记录的数据使得对临床发现和治疗结果进行回顾性评估成为可能。在观察期开始时,27例患者接受了双眼光凝治疗,16例接受了单眼光凝治疗。9例患者在一开始就已失明。在观察期内失明的13例患者中,有10例未对患眼进行光凝治疗。接受光凝治疗的3例患者(5只眼)从失明到死亡的时间跨度(1.5年)比未接受治疗的糖尿病患者(4.3年)短。所有23例初始视力得以维持的患者都接受了光凝治疗。严重糖尿病视网膜病变或肾病的存在对光凝治疗的结果产生了不利影响。