Fischer F
Dtsch Z Verdau Stoffwechselkr. 1982;42(2-3):94-8.
General experience shows that proliferative diabetic retinopathy leads to blindness within only a short time, in spite of short-term improvements in the clinical picture. Long-lasting remission can occur, but seldom for more than a few years. We have observed 3 patients with proliferative retinopathy in whom remission continued for more than 15 years, in one case even lasting over 20 years. Good, useful vision was maintained during all this time. This was only true of one eye, however, while the other eye rapidly became blind. Of the other forms of angiopathy, little coronary heart disease and no peripheral vascular disease was observed in these patients. There were also no signs of nephropathy, i.e. diabetes-specific glomerular sclerosis. Thus, the total picture of angiopathy seems to be benign. The remission of the retinopathy seems to be in accord with this general trend, although it can perhaps be partly explained by unknown local factors in the eye itself.
一般经验表明,尽管增殖性糖尿病视网膜病变的临床表现有短期改善,但仍会在短时间内导致失明。持久缓解可能会出现,但很少超过数年。我们观察到3例增殖性视网膜病变患者,其缓解持续超过15年,其中1例甚至持续超过20年。在此期间,一直保持着良好、有用的视力。然而,这仅适用于一只眼睛,而另一只眼睛迅速失明。在这些患者中,未观察到其他形式的血管病变,很少有冠心病,也没有外周血管疾病。也没有肾病的迹象,即糖尿病特异性肾小球硬化。因此,血管病变的总体情况似乎是良性的。视网膜病变的缓解似乎与这一总体趋势一致,尽管这可能部分是由眼睛本身未知的局部因素所解释。