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低蛋白饮食对慢性肾衰竭患者血清铜蓝蛋白和转铁蛋白水平的影响。

The effect of a low-protein diet on serum levels of ceruloplasmin and transferrin in patients with chronic renal failure.

作者信息

Marecek Z, Vulterinová M, Skála I, Pechar J, Doberský P, Schück O, Nádvorníková H, Heyrovský I

出版信息

Clin Nephrol. 1978 Jan;9(1):38-40.

PMID:630743
Abstract

In patients with chronic renal failure the administration of a diet providing 20 g protein per day for five weeks caused a significant rise in the serum ceruloplasmin level. A low dietary copper content (0.8 mg/day) may have been the limiting factor for any further rise of the ceruloplasmin level. The rise of ceruloplasmin was associated with a continuous decline of total iron binding capacity. The temporarily raised serum iron levels and the continuous decline of unsaturated iron binding capacity suggested enhanced iron mobilization caused by the raised ceruloplasmin level. The rise of ceruloplasmin correlated with the decline of UIBC.

摘要

在慢性肾衰竭患者中,给予每日提供20克蛋白质的饮食持续五周后,血清铜蓝蛋白水平显著升高。低膳食铜含量(0.8毫克/天)可能是铜蓝蛋白水平进一步升高的限制因素。铜蓝蛋白的升高与总铁结合力的持续下降有关。血清铁水平暂时升高以及不饱和铁结合力持续下降表明,铜蓝蛋白水平升高导致铁动员增强。铜蓝蛋白的升高与未饱和铁结合力的下降相关。

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Clin Nephrol. 1978 Jan;9(1):38-40.
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