接种疫苗儿童体内的百日咳凝集素：佐剂可带来更好的反应。
Pertussis agglutinins in vaccinated children: better response with adjuvant.
作者信息
Preston N W, Mackay R I, Bamford F N, Crofts J E, Burland W L
出版信息
J Hyg (Lond). 1974 Aug;73(1):119-25. doi: 10.1017/s0022172400023913.
Children were immunized with a single batch of pertussis vaccine, either adsorbed on aluminium hydroxide or plain. With a primary course of three injections, adsorbed vaccine produced higher titres of pertussis agglutinins in the serum than did plain vaccine. There was no obvious difference in response between those who received the three doses at intervals of 1-2 months, starting at 3-4 months of age, and those in whom the third dose was delayed until about 6 months after the second, but the number of children in each group was small.
儿童接种了一批单一的百日咳疫苗，该疫苗要么吸附于氢氧化铝上，要么为普通疫苗。经过三针的基础免疫疗程后，吸附疫苗在血清中产生的百日咳凝集素滴度高于普通疫苗。对于那些在3至4月龄开始每隔1至2个月接种三剂疫苗的儿童，与那些将第三剂疫苗推迟至第二剂接种后约6个月的儿童相比，二者的反应没有明显差异，但每组儿童的数量较少。
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