Abbott J D, Preston N W, Mackay R I
Br Med J. 1971 Jan 9;1(5740):86-8. doi: 10.1136/bmj.1.5740.86.
Children were immunized with plain pertussis vaccine made by three manufacturers in 1967. After a primary course of three injections at monthly intervals, starting at 3-4 months of age, the agglutinin response was poor. Even after a "booster" dose, given five months later, not all of the vaccines had stimulated a response to all three pertussis agglutinogens. A further investigation with current vaccines of different kinds administered according to more than one schedule is recommended.
1967年,孩子们接种了由三家制造商生产的普通百日咳疫苗。在从3至4个月大开始,每月间隔进行三次注射的基础免疫疗程后,凝集素反应较差。即使在五个月后给予“加强”剂量,并非所有疫苗都能刺激对所有三种百日咳凝集原产生反应。建议根据不止一种接种程序,对目前不同种类的疫苗进行进一步调查。