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儿童对百日咳疫苗接种的凝集素反应。

Agglutinin response to pertussis vaccination in the child.

作者信息

Abbott J D, Preston N W, Mackay R I

出版信息

Br Med J. 1971 Jan 9;1(5740):86-8. doi: 10.1136/bmj.1.5740.86.

Abstract

Children were immunized with plain pertussis vaccine made by three manufacturers in 1967. After a primary course of three injections at monthly intervals, starting at 3-4 months of age, the agglutinin response was poor. Even after a "booster" dose, given five months later, not all of the vaccines had stimulated a response to all three pertussis agglutinogens. A further investigation with current vaccines of different kinds administered according to more than one schedule is recommended.

摘要

1967年,孩子们接种了由三家制造商生产的普通百日咳疫苗。在从3至4个月大开始,每月间隔进行三次注射的基础免疫疗程后,凝集素反应较差。即使在五个月后给予“加强”剂量,并非所有疫苗都能刺激对所有三种百日咳凝集原产生反应。建议根据不止一种接种程序,对目前不同种类的疫苗进行进一步调查。

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Pertussis vaccines, epidemiology and evolution.百日咳疫苗、流行病学和进化。
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Efficacy of whooping-cough vaccines.百日咳疫苗的功效。
Br Med J. 1973 May 26;2(5864):485-6. doi: 10.1136/bmj.2.5864.485-c.
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Editorial: Vaccination against whooping cough.社论:百日咳疫苗接种
Br Med J. 1974 Aug 31;3(5930):539-40. doi: 10.1136/bmj.3.5930.539.

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