对从不同生态位分离得到的拉克罗斯病毒进行比较，并对加利福尼亚脑炎血清群病毒和其他布尼亚病毒的结构成分进行分析。

A comparison of La Crosse virus isolated obtained from different ecological niches and an analysis of the structural components of California encephalitis serogroup viruses and other bunyaviruses.

作者信息

El Said L H, Vorndam V, Gentsch J R, Clewley J P, Calisher C H, Klimas R A, Thompson W H, Grayson M, Trent D W, Bishop D H

出版信息

Am J Trop Med Hyg. 1979 Mar;28(2):364-86. doi: 10.4269/ajtmh.1979.28.364.

DOI:10.4269/ajtmh.1979.28.364

PMID:453439

Abstract

Analyses of the oligonucleotide fingerprints of the three genome ribonucleic acid (RNA) species of 11 isolates of La Crosse (LAC) virus, obtained from various ecological niches in the northern United States and compared to those of prototype LAC virus, showed that in each place from which these isolates were obtained LAC variants and varieties were present with related, but distinguishable, nucleotide sequences for their large, medium, or small RNA species. The RNA genomes of prototypes trivittatus (TVT), snowshoe hare (SSH), Tahyna (TAH), and Lumbo (a variety of TAH) viruses of the California encephalitis (CE) serogroup, and Guaroa of the Bunyamwera serogroup also consist of three RNA species, each with unique and distinguishable nucleotide sequences which bear little resemblance to those of the LAC virus isolates. The virions of CE group viruses (CE, Jamestown Canyon, Keystone, LAC, Melao, SSH, TVT, TAH viruses and South River, an unregistered virus) have three major viral polypeptides, designated G1, G2, and N.

摘要

对从美国北部不同生态位获得的11株拉克罗斯（LAC）病毒的三种基因组核糖核酸（RNA）种类的寡核苷酸指纹图谱进行分析，并与原型LAC病毒的图谱进行比较，结果显示，在获得这些分离株的每个地方，LAC病毒变种和品种都具有与其大、中或小RNA种类相关但可区分的核苷酸序列。加利福尼亚脑炎（CE）血清群的原型三带喙库蚊（TVT）、雪兔（SSH）、塔希纳（TAH）和伦博（TAH的一个变种）病毒，以及本扬韦拉血清群的瓜罗阿病毒的RNA基因组也由三种RNA种类组成，每种都有独特且可区分的核苷酸序列，与LAC病毒分离株的序列几乎没有相似之处。CE血清群病毒（CE、詹姆斯敦峡谷、基斯通、LAC、梅劳、SSH、TVT、TAH病毒以及未注册的南河病毒）的病毒粒子有三种主要病毒多肽，分别命名为G1、G2和N。