Arunagiri C K, Perera L P, Abeykoon S B, Peiris J S
Department of Microbiology, Faculty of Medicine, University of Peradeniya, Sri Lanka.
Am J Trop Med Hyg. 1991 Sep;45(3):377-82. doi: 10.4269/ajtmh.1991.45.377.
A seroepidemiologic study of California (CAL) serogroup viruses (genus bunyavirus, family Bunyaviridae) was carried out on 952 human and 1,834 animal sera collected from different ecological zones of Sri Lanka (latitudes 5-10 degrees N, longitudes 79-82 degrees E). The sera were screened for neutralizing antibody to Lumbo (LUM), snowshoe hare (SSH), and trivittatus (TVT) viruses by plaque neutralization tests on Vero cells. Of 2,786 sera screened, 262 (9.5%) had antibody to one or more viruses Twenty-two sera, selected to represent different species of origin and reaction profiles, were titrated against nine CAL viruses: LUM, SSH, TVT, Tahyna (TAH), California encephalitis (CE), La Crosse (LAC), Inkoo (INK), Melao (MEL), and Guaroa (GRO). Results suggested that there were multiple CAL viruses active in Sri Lanka, one or more of them closely related to LUMBO and SSH viruses, and another related to MELAO virus. These viruses were active in both the wet and dry zones of the country, and infected humans as well as a range of domestic livestock.
对从斯里兰卡不同生态区（北纬5 - 10度，东经79 - 82度）采集的952份人类血清和1834份动物血清进行了加利福尼亚（CAL）血清群病毒（布尼亚病毒属，布尼亚病毒科）的血清流行病学研究。通过在Vero细胞上进行蚀斑中和试验，筛查血清中针对伦波（LUM）、雪兔（SSH）和三带（TVT）病毒的中和抗体。在筛查的2786份血清中，262份（9.5%）对一种或多种病毒有抗体。选择22份代表不同来源物种和反应谱的血清，针对9种CAL病毒进行滴定：LUM、SSH、TVT、塔伊纳（TAH）、加利福尼亚脑炎（CE）、拉克罗斯（LAC）、因库奥（INK）、梅拉奥（MEL）和瓜罗阿（GRO）。结果表明，在斯里兰卡有多种CAL病毒活跃，其中一种或多种与伦波病毒和雪兔病毒密切相关，另一种与梅拉奥病毒相关。这些病毒在该国的湿润和干旱地区均有活跃，并且感染人类以及一系列家畜。
