Khan A Q, Talibi S A
Bull World Health Organ. 1972;46(6):783-92.
A longitudinal epidemiological study was carried out in a hyperendemic malarious area of East Pakistan. Transmission of malaria was observed with two peaks, one in the premonsoon period, the other in the pre-winter period. New infections occurred in 51.7% of the infants surveyed who were 2 months old or under when first examined: there were frequent superinfections. The maternal immunity passively transferred to the infants did not play a significant role in restricting the development of the asexual erythrocytic stage or that of gametocytes, as indicated by the fact that the average parasite density and the gametocyte counts were highest in the 0-2-month age group and declined with increasing age. Mosquitos were collected for identification and for dissection to determine parity, the sporozoite rate, the vectorial capacity, and other basic indices. An. minimus was the principal vector, but An. leucosphyrous was also found to be positive.
在东巴基斯坦的一个疟疾高度流行地区开展了一项纵向流行病学研究。观察到疟疾传播有两个高峰，一个在季风前期，另一个在初冬期。在首次检查时年龄为2个月及以下的接受调查婴儿中，51.7%发生了新感染：频繁出现重复感染。被动转移给婴儿的母体免疫力在限制无性红细胞期或配子体发育方面未发挥重要作用，这一事实表明，0至2个月龄组的平均寄生虫密度和配子体计数最高，且随年龄增长而下降。收集蚊子进行鉴定和解剖，以确定其孕卵情况、子孢子率、传播能力及其他基本指标。微小按蚊是主要传播媒介，但也发现白跗按蚊呈阳性。
