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囊性纤维化与听力损失。

Cystic fibrosis and hearing loss.

作者信息

Forman-Franco B, Abramson A L, Gorvoy J D, Stein T

出版信息

Arch Otolaryngol. 1979 Jun;105(6):338-42. doi: 10.1001/archotol.1979.00790180036007.

DOI:10.1001/archotol.1979.00790180036007
PMID:454286
Abstract

The mucosal epithelium of the middle ear and Eustachian tube is in direct continuity with the upper respiratory tract. Since the otolaryngological aspects of cystic fibrosis (CF) are dominated by involvement of the paranasal sinuses, it might be assumed that children with CF would be expected to have a higher than usual incidence of middle ear disease. Eighty patients who were afflicted with CF had audiological evaluations, which consisted of hearing threshold levels (250 to 8,000 Hz) and speech and impedance audiometry. We found no greater incidence of a conductive or sensorineural hearing loss in patients with CF when compared with a normal age-adjusted population.

摘要

中耳和咽鼓管的黏膜上皮与上呼吸道直接相连。由于囊性纤维化(CF)的耳鼻喉科表现主要由鼻窦受累主导,因此可能会认为CF患儿中耳疾病的发病率会高于正常水平。80例CF患儿接受了听力评估,包括听阈水平(250至8000赫兹)以及言语和阻抗测听。与年龄匹配的正常人群相比,我们发现CF患者中传导性或感音神经性听力损失的发生率并无更高。

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引用本文的文献

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Am J Audiol. 2021 Oct 11;30(3S):834-853. doi: 10.1044/2020_AJA-20-00059. Epub 2021 Jan 19.
2
Changes in the inner ear structures in cystic fibrosis patients.囊性纤维化患者内耳结构的变化。
Int J Pediatr Otorhinolaryngol. 2017 Jan;92:108-114. doi: 10.1016/j.ijporl.2016.11.013. Epub 2016 Nov 16.
3
cAMP-stimulated Cl- secretion is increased by glucocorticoids and inhibited by bumetanide in semicircular canal duct epithelium.
在半规管导管上皮中,环磷酸腺苷(cAMP)刺激的氯离子分泌会因糖皮质激素而增加,并被布美他尼抑制。
BMC Physiol. 2013 Mar 27;13:6. doi: 10.1186/1472-6793-13-6.
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Side effects of aminoglycosides on the kidney, ear and balance in cystic fibrosis.氨基糖苷类药物对囊性纤维化患者的肾脏、耳朵和平衡的副作用。
Thorax. 2010 Jul;65(7):654-8. doi: 10.1136/thx.2009.131532.
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Sinusitis in patients with cystic fibrosis.囊性纤维化患者的鼻窦炎
Eur Arch Otorhinolaryngol. 1995;252(4):191-6. doi: 10.1007/BF00179910.
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Nasal polyposis, opaque paranasal sinuses and usually normal hearing: the otorhinolaryngological features of cystic fibrosis.鼻息肉病、鼻窦混浊且听力通常正常:囊性纤维化的耳鼻喉科特征。
J R Soc Med. 1986;79 Suppl 12(Suppl 12):23-6.
7
ENT surgery and cystic fibrosis.耳鼻喉科手术与囊性纤维化
J R Soc Med. 1992;85 Suppl 19(Suppl 19):29-32.