肯尼亚地方性和非地方性昏睡病地区人群血液IgM水平模式的观察。

Observations on the patterns of blood IgM levels in the populations of endemic and nonendemic sleeping sickness areas in Kenya.

作者信息

Binz G, Watson H J

出版信息

Bull World Health Organ. 1972;47(6):757-67.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2480936/

Abstract

Increased levels of serum immunoglobulin M (IgM) may be related to a wide range of antigenic stimuli provided by a variety of infections to which people are repeatedly exposed. Most, if not all, of the natural antibodies against bacterial and cellular antigens have been found to belong to the IgM class. It is known that IgM levels in the blood increase in trypanosomiasis but it is not possible to demonstrate trypanosomes in all persons who show raised IgM levels in serological surveys in an endemic sleeping sickness area. Although survey data are limited, this paper discusses the usefulness of IgM tests as an aid to the detection of Trypanosoma rhodesiense infections.

摘要

血清免疫球蛋白M（IgM）水平升高可能与人们反复接触的各种感染所提供的广泛抗原刺激有关。已发现大多数（如果不是全部）针对细菌和细胞抗原的天然抗体属于IgM类别。众所周知，在锥虫病中血液中的IgM水平会升高，但在昏睡病流行地区的血清学调查中，不可能在所有IgM水平升高的人中都检测到锥虫。尽管调查数据有限，但本文讨论了IgM检测作为辅助检测罗德西亚锥虫感染的有用性。

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The role of game animals in the maintenance of endemic and enzootic trypanosomiases in the Lambwe Valley, South Nyanza District, Kenya.肯尼亚南尼亚萨区兰贝谷地区猎物在地方性和动物流行性锥虫病传播中的作用

Bull World Health Organ. 1972;47(6):735-46.

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Trypanosomiasis in domestic livestock in the Lambwe Valley area and a field evaluation of various diagnostic techniques.兰贝谷地区家畜的锥虫病及各种诊断技术的现场评估

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A history of Rhodesian sleeping sickness in the Lambwe Valley.兰贝谷的罗德西亚昏睡病病史。

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