Latner A L, Longstaff E, Turner G A
Br J Cancer. 1974 Jul;30(1):60-7. doi: 10.1038/bjc.1974.113.
A malignant invasive fibrosarcoma in hamsters and a malignant mammary carcinoma in mice were each challenged with the broad spectrum proteinase inhibitor aprotinin (Trasylol). In both tumour systems, significant anti-tumour effects of aprotinin were observed. Variations in the site and dosage of aprotinin application were made in an attempt to improve the chemotherapeutic response.