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霍乱中的胃部异常:流行病学与临床考量

Gastric abnormalities in cholera: epidemiological and clinical considerations.

作者信息

Schiraldi O, Benvestito V, Di Bari C, Moschetta R, Pastore G

出版信息

Bull World Health Organ. 1974;51(4):349-52.

Abstract

The anatomofunctional status of the stomach was studied in cholera patients during the outbreak in Bari, Italy, in 1973. Of a total of 70 patients examined, 24 were found to have undergone gastric resection for ulcer in the past. Stomach secretions induced by fasting and histamine stimulation were studied in 30 patients, the majority of whom showed achlorhydria and other disturbances of gastric secretion. These abnormalities not only predisposed the patients to cholera infection but shortened the incubation period. The clinical course and severity of the disease were also related to the degree of gastric damage, the most serious cases occurring in gastrectomized patients.

摘要

1973年意大利巴里霍乱疫情爆发期间,对霍乱患者的胃解剖功能状态进行了研究。在总共检查的70名患者中,发现有24人过去因溃疡接受过胃切除术。对30名患者的空腹和组胺刺激诱导的胃分泌物进行了研究,其中大多数患者表现为胃酸缺乏和其他胃分泌紊乱。这些异常不仅使患者易感染霍乱,还缩短了潜伏期。疾病的临床病程和严重程度也与胃损伤程度有关,最严重的病例发生在胃切除患者中。

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