Barui R K, Mosley W H, McCormack W M
Bull World Health Organ. 1972;46(2):257-62.
The relative effectiveness of daily rectal-swab cultures and cultures of purged stools in detecting inapparent infections of Vibrio cholerae were compared in family contacts of cholera patients. In one study of 187 contacts, a combination of purging by various methods plus 5 daily swabs detected 50 infections. Only 27 (54%) were detected by the purge alone, while 47 (94%) were detected by 5 daily rectal-swab cultures. In a second study of two groups of family contacts, purging on the first day did not appear to influence significantly the number of positive rectal-swab cultures obtained during the 4 subsequent days. The relative inefficiency of purging in detecting the inapparent infections among cholera contacts, as compared with its reported efficacy in the chronic convalescent carrier, probably reflects a basic difference in the pathogenesis and site of infection in these different conditions.
在霍乱患者的家庭接触者中,比较了每日直肠拭子培养和净化粪便培养在检测霍乱弧菌隐性感染方面的相对有效性。在一项针对187名接触者的研究中,通过各种方法进行净化并每日进行5次拭子检测,共检测出50例感染。仅通过净化检测出27例(54%),而通过每日5次直肠拭子培养检测出47例(94%)。在另一项针对两组家庭接触者的研究中,第一天进行净化似乎对随后4天获得的直肠拭子培养阳性数量没有显著影响。与在慢性恢复期带菌者中报告的净化功效相比,净化在检测霍乱接触者隐性感染方面相对低效,这可能反映了这些不同情况下发病机制和感染部位的根本差异。