菲律宾霍乱埃尔托型的研究。3. 霍乱患者家庭接触者之间的感染传播。
Studies of cholera El Tor in the Philippines. 3. Transmission of infection among household contacts of cholera patients.
作者信息
Tamayo J F, Mosley W H, Alvero M G, Joseph P R, Gomez C Z, Montague T, Dizon J J, Henderson D A
出版信息
Bull World Health Organ. 1965;33(5):645-9.
As part of a broad epidemiological investigation of cholera El Tor in the Philippines, the authors cultured rectal swabs obtained from the household contacts of cholera patients hospitalized in the Negros Occidental Provincial Hospital from August through October 1962. Additional infected persons were found in 25 (60%) of the 42 households with confirmed cases and in 55 (18%) of 302 household contacts of confirmed patients. Since only five of the 55 infected household contacts developed illness severe enough to require hospitalization, it was apparent that those with severe illness accounted for but a small proportion of the total infections. Asymptomatic infections were rarely found outside the households with proven cases, suggesting that close person-to-person contact was necessary for the spread of infection. Asymptomatic carriers as well as symptomatic patients appeared to play significant roles in the transmission of infection.
作为菲律宾霍乱埃尔托型广泛流行病学调查的一部分，作者对1962年8月至10月在西内格罗斯省医院住院的霍乱患者家庭接触者的直肠拭子进行了培养。在42例确诊病例的家庭中，有25户（60%）发现了其他感染者；在确诊患者的302名家庭接触者中，有55人（18%）被感染。由于55名受感染的家庭接触者中只有5人病情严重到需要住院治疗，显然重病患者仅占总感染人数的一小部分。在有确诊病例的家庭之外，很少发现无症状感染者，这表明感染传播需要密切的人际接触。无症状携带者以及有症状的患者似乎在感染传播中都起着重要作用。
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