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具有抗体形成能力的骨髓细胞的囊起源。

Bursal origin of bone marrow cells with competence for antibody formation.

作者信息

Ivanyi J, Murgatroyd L B, Lydyard P M

出版信息

Immunology. 1972 Jul;23(1):107-11.

PMID:4558092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1407779/
Abstract

The impaired antibody response of neonatally bursectomized chickens was restored by bone marrow cells from normal—but not from bursectomized—syngeneic donors. Chimaerism of donor cells in the recipients was demonstrated using the sex chromosomal marker. Attempts to substitute autologous bursal cell suspensions for the bursa were unsuccessful. It is concluded that B lymphocytes in chicken bone marrow have matured in the bursa.

摘要

新生期切除法氏囊的鸡所受损的抗体反应,可通过来自正常同基因供体(而非切除法氏囊的同基因供体)的骨髓细胞得以恢复。利用性染色体标记证明了受体中存在供体细胞的嵌合现象。用自体法氏囊细胞悬液替代法氏囊的尝试未获成功。得出的结论是,鸡骨髓中的B淋巴细胞是在法氏囊中成熟的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e44f/1407779/96ae9303e762/immunology00342-0117-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e44f/1407779/96ae9303e762/immunology00342-0117-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e44f/1407779/96ae9303e762/immunology00342-0117-a.jpg

相似文献

1
Bursal origin of bone marrow cells with competence for antibody formation.具有抗体形成能力的骨髓细胞的囊起源。
Immunology. 1972 Jul;23(1):107-11.
2
Bursal and postbursal stem cells in chicken. Functional characteristics.鸡的法氏囊及法氏囊后干细胞。功能特性。
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Adoptive transfer of antibody formation by various cell types in chickens and an attempt to demonstrate synergism.鸡体内不同细胞类型抗体形成的过继转移及协同作用的验证尝试。
Folia Biol (Praha). 1974;20(4):262-70.
4
Ontogeny of bursal function in chicken. II. Postembryonic stem cell for humoral immunity.鸡法氏囊功能的个体发生。II. 体液免疫的胚后干细胞。
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Bursal and postbursal cells in chicken. Occurrence of postbursal cells in bone marrow, thymus and spleen.鸡的法氏囊及法氏囊后细胞。骨髓、胸腺和脾脏中法氏囊后细胞的存在情况。
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Ontogeny of bursal function in chicken. I. Embryonic stem cell for humoral immunity.鸡法氏囊功能的个体发生。I. 体液免疫的胚胎干细胞。
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引用本文的文献

1
Direct stimulation of lymphoid tissue of the chicken. 3. Haemagglutinin production, haemolysin-forming cells and changes in lymphoid tissues following injection of guinea-pig erythrocytes into the bone marrow.鸡淋巴组织的直接刺激。3. 将豚鼠红细胞注射到骨髓后血凝素的产生、溶血素形成细胞及淋巴组织的变化。
Immunology. 1973 Oct;25(4):663-74.
2
Ontogeny of B cells in the chicken. I. Sequential development of clonal diversity in the bursa.鸡B细胞的个体发生。I. 法氏囊中克隆多样性的顺序发育。
J Exp Med. 1976 Jul 1;144(1):79-97. doi: 10.1084/jem.144.1.79.
3
Delayed-type skin reactions in bursectomized or thymectomized chickens.

本文引用的文献

1
Experimental studies on the development of the bursa of Fabricius.法氏囊发育的实验研究。
Dev Biol. 1966 Aug;14(1):40-51. doi: 10.1016/0012-1606(66)90004-2.
2
Absence of antibody production in the bursa of Fabricius.法氏囊中无抗体产生。
Nature. 1965 Jul 31;207(996):491-3. doi: 10.1038/207491a0.
3
Karyotype studies on Gallus domesticus.家鸡的核型研究。
法氏囊切除或胸腺切除鸡的迟发型皮肤反应。
Experientia. 1977 Aug 15;33(8):1105-6. doi: 10.1007/BF01945997.
4
The bursal origin of an immunocompetent cell for antibody formation in the chicken.鸡体内产生抗体的免疫活性细胞的法氏囊起源。
Immunology. 1975 Aug;29(2):307-18.
5
Cell transplantation into immunodeficient chicken embryos. Reconstituting capacity of cells from the yolk sac at different stages of development and from the liver, thymus, bursa of Fabricius, spleen and bone marrow of 15-day embryos.将细胞移植到免疫缺陷鸡胚中。来自不同发育阶段卵黄囊以及15日龄胚胎的肝脏、胸腺、法氏囊、脾脏和骨髓的细胞的重建能力。
Immunology. 1977 Apr;32(4):467-74.
Chromosoma. 1965 May 26;16(5):601-8. doi: 10.1007/BF00326975.
4
Maturation of hemolysin-producing cell clones. II. The appearance and localization of precursor units in lymphoid tissues of neonatal mice.产溶血素细胞克隆的成熟。II. 新生小鼠淋巴组织中前体单位的出现及定位。
J Exp Med. 1970 Jun 1;131(6):1261-70. doi: 10.1084/jem.131.6.1261.
5
Antigen binding cells in embryonic chicken bursa and thymus.胚胎期鸡法氏囊和胸腺中的抗原结合细胞。
Nat New Biol. 1971 Feb 17;229(7):210-1. doi: 10.1038/newbio229210a0.
6
Impairment of humoral antibody response in neonatally thymectomized and irradiated chickens.新生期胸腺切除并经照射的鸡的体液抗体反应受损。
Eur J Immunol. 1971 Aug;1(4):227-30. doi: 10.1002/eji.1830010402.
7
Functional deficiency of autologous implants of the bursa of Fabricius in chickens.鸡法氏囊自体植入物的功能缺陷
Transplantation. 1971 Jan;11(1):71-7. doi: 10.1097/00007890-197101000-00010.
8
Cellular mechanisms of escape from immunological tolerance.逃避免疫耐受的细胞机制。
Immunology. 1972 Feb;22(2):247-57.
9
Transfer of antibody production with cells from bursa of Fabricius.用法氏囊细胞进行抗体产生的转移。
J Exp Med. 1970 Jul 1;132(1):134-47. doi: 10.1084/jem.132.1.134.
10
Long-term reconstitution of bursectomized chickens.法氏囊切除鸡的长期重建
J Immunol. 1971 Aug;107(2):598-600.