具有抗体形成能力的骨髓细胞的囊起源。
Bursal origin of bone marrow cells with competence for antibody formation.
作者信息
Ivanyi J, Murgatroyd L B, Lydyard P M
出版信息
Immunology. 1972 Jul;23(1):107-11.
Abstract
The impaired antibody response of neonatally bursectomized chickens was restored by bone marrow cells from normal—but not from bursectomized—syngeneic donors. Chimaerism of donor cells in the recipients was demonstrated using the sex chromosomal marker. Attempts to substitute autologous bursal cell suspensions for the bursa were unsuccessful. It is concluded that B lymphocytes in chicken bone marrow have matured in the bursa.
摘要
新生期切除法氏囊的鸡所受损的抗体反应，可通过来自正常同基因供体（而非切除法氏囊的同基因供体）的骨髓细胞得以恢复。利用性染色体标记证明了受体中存在供体细胞的嵌合现象。用自体法氏囊细胞悬液替代法氏囊的尝试未获成功。得出的结论是，鸡骨髓中的B淋巴细胞是在法氏囊中成熟的。
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