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通过表面冷却进行肾脏保存:130例移植分析

Kidney preservation by surface cooling: analysis of 130 transplants.

作者信息

Hulme B, Snell M E, Kenyon J R, Owen K, Peart W S

出版信息

Br Med J. 1972 Oct 21;4(5833):139-41. doi: 10.1136/bmj.4.5833.139.

Abstract

An analysis of 130 consecutive cadaveric renal transplants has shown the effectiveness of simple surface cooling of organs before transplantation. The primary graft failure rate was 10%, and kidneys could be stored for periods of up to 12 hours including warm ischaemia times of 150 minutes. Forty-eight patients received haemodialysis before transplantation and 78 patients received peritoneal dialysis. There were significant differences in the incidence of tubular necrosis in the two groups: these may have been linked to the differences in fluid and osmotic load presented to the transplants.

摘要

对130例连续的尸体肾移植进行分析,结果显示移植前对器官进行简单的表面降温是有效的。原发性移植肾无功能发生率为10%,肾脏可保存长达12小时,包括150分钟的热缺血时间。48例患者在移植前接受血液透析,78例患者接受腹膜透析。两组肾小管坏死的发生率存在显著差异:这可能与移植时所承受的液体和渗透压负荷的差异有关。

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本文引用的文献

1
Human cadaveric renal transplantation. Report of twenty cases.人类尸体肾移植。20例报告。
Br Med J. 1965 Dec 11;2(5475):1387-94. doi: 10.1136/bmj.2.5475.1387.
2
Storage and transport of 83 human kidneys by simple hypothermia.
Transplantation. 1971 Nov;12(5):348-52. doi: 10.1097/00007890-197111000-00002.
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Preservation and transplantation of human cadaver kidneys: a two-year experience.
Ann Surg. 1970 Sep;172(3):394-404. doi: 10.1097/00000658-197009000-00009.
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The cadaveric kidney in clinical transplantation.临床移植中的尸体肾。
Scand J Urol Nephrol. 1968;2(1):15-23. doi: 10.3109/00365596809133557.
9
Cadaveric renal transplantation: a technique for donor kidney removal.尸体肾移植:供肾摘取技术。
Br J Urol. 1968 Oct;40(5):515-21. doi: 10.1111/j.1464-410x.1968.tb11842.x.
10

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