Hulme B, Snell M E, Kenyon J R, Owen K, Peart W S
Br Med J. 1972 Oct 21;4(5833):139-41. doi: 10.1136/bmj.4.5833.139.
An analysis of 130 consecutive cadaveric renal transplants has shown the effectiveness of simple surface cooling of organs before transplantation. The primary graft failure rate was 10%, and kidneys could be stored for periods of up to 12 hours including warm ischaemia times of 150 minutes. Forty-eight patients received haemodialysis before transplantation and 78 patients received peritoneal dialysis. There were significant differences in the incidence of tubular necrosis in the two groups: these may have been linked to the differences in fluid and osmotic load presented to the transplants.
对130例连续的尸体肾移植进行分析,结果显示移植前对器官进行简单的表面降温是有效的。原发性移植肾无功能发生率为10%,肾脏可保存长达12小时,包括150分钟的热缺血时间。48例患者在移植前接受血液透析,78例患者接受腹膜透析。两组肾小管坏死的发生率存在显著差异:这可能与移植时所承受的液体和渗透压负荷的差异有关。