氨、甲胺、氯喹和亮抑酶肽对离体大鼠肝细胞中蛋白质降解溶酶体途径的抑制作用。 - Suppr

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超能文献

Inhibition of the lysosomal pathway of protein degradation in isolated rat hepatocytes by ammonia, methylamine, chloroquine and leupeptin.

作者信息

Seglen P O, Grinde B, Solheim A E

出版信息

Eur J Biochem. 1979 Apr 2;95(2):215-25. doi: 10.1111/j.1432-1033.1979.tb12956.x.

DOI:10.1111/j.1432-1033.1979.tb12956.x

PMID:456353

Abstract

摘要

相似文献

Inhibition of the lysosomal pathway of protein degradation in isolated rat hepatocytes by ammonia, methylamine, chloroquine and leupeptin.氨、甲胺、氯喹和亮抑酶肽对离体大鼠肝细胞中蛋白质降解溶酶体途径的抑制作用。

Eur J Biochem. 1979 Apr 2;95(2):215-25. doi: 10.1111/j.1432-1033.1979.tb12956.x.

The effect of ammonia, chloroquine, leupeptin, colchicine and cytochalasin B on degradation of high density lipoproteins in isolated rat hepatocytes.氨、氯喹、亮抑酶肽、秋水仙碱和细胞松弛素B对分离的大鼠肝细胞中高密度脂蛋白降解的影响。

Exp Cell Res. 1980 Nov;130(1):127-35. doi: 10.1016/0014-4827(80)90049-x.

Effects of amino acids, ammonia and leupeptin on protein synthesis and degradation in isolated rat hepatocytes.氨基酸、氨和亮抑蛋白酶肽对分离的大鼠肝细胞中蛋白质合成与降解的影响。

Biochem J. 1978 Aug 15;174(2):469-74. doi: 10.1042/bj1740469.

Effects of lysosomal inhibitors on 125I-insulin and 125I-asialofetuin degradation by the isolated, perfused rat liver and isolated rat hepatocytes.溶酶体抑制剂对分离的灌注大鼠肝脏和分离的大鼠肝细胞降解125I-胰岛素及125I-去唾液酸胎球蛋白的影响。

Diabetes. 1985 May;34(5):446-51. doi: 10.2337/diab.34.5.446.

Differential effects of proteinase inhibitors and amines on the lysosomal and non-lysosomal pathways of protein degradation in isolated rat hepatocytes.蛋白酶抑制剂和胺类对分离的大鼠肝细胞中蛋白质降解的溶酶体和非溶酶体途径的不同作用。

Biochim Biophys Acta. 1980 Sep 17;632(1):73-86. doi: 10.1016/0304-4165(80)90250-0.

Effect of amino acids and cycloheximide on changes caused by vinblastine, leupeptin and methylamine in the autophagic/lysosomal system of mouse hepatocytes in vivo.氨基酸和环己酰亚胺对长春碱、亮抑酶肽和甲胺在体内小鼠肝细胞自噬/溶酶体系统中所引起变化的影响。

Exp Cell Res. 1985 Mar;157(1):83-94. doi: 10.1016/0014-4827(85)90154-5.

Structural and physical changes in lysosomes from isolated rat hepatocytes treated with methylamine.用甲胺处理的离体大鼠肝细胞溶酶体的结构和物理变化。

Biochim Biophys Acta. 1983 Oct 25;763(3):284-91. doi: 10.1016/0167-4889(83)90136-2.

Effect of leupeptin on the intracellular degradation of asialofetuin in isolated rat hepatocytes.亮抑酶肽对离体大鼠肝细胞中去唾液酸胎球蛋白细胞内降解的影响。

Acta Biol Med Ger. 1981;40(10-11):1599-602.

Comparison of different autophagic vacuoles with regard to ultrastructure, enzymatic composition, and degradation capacity--formation of crinosomes.不同自噬泡在超微结构、酶组成和降解能力方面的比较——毛体的形成。

Exp Mol Pathol. 1987 Dec;47(3):346-62. doi: 10.1016/0014-4800(87)90018-9.

Participation of lysosomes in basal proteolysis in perfused rat liver. Discrepancy between leupeptin-induced lysosomal enlargement and inhibition of proteolysis.溶酶体参与灌注大鼠肝脏的基础蛋白水解作用。亮肽素诱导的溶酶体增大与蛋白水解抑制之间的差异。

Exp Cell Res. 1985 May;158(1):257-62. doi: 10.1016/0014-4827(85)90448-3.

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