Puurunen J
Eur J Pharmacol. 1979 Apr 15;55(2):207-9. doi: 10.1016/0014-2999(79)90394-7.
When the osmolarity of intragastric instillates was constant (200 mosmole/l) the changes in their hydrogen ion concentrations (maximally from 0.01 to 100 mM) did not significantly affect pepsinogen secretion in anaesthetised rats. Solutions of 100 mM HCl, 100 mM NaCl and 150 mM sucrose all produced a similar stimulation of pepsinogen secretion. The results do not support the view that the gastric mucosa contains receptors sensitive to hydrogen ions regulating pepsinogen secretion under physiological conditions.
当胃内灌流液的渗透压恒定（200毫渗摩尔/升）时，其氢离子浓度的变化（最大变化范围为0.01至100毫摩尔/升）对麻醉大鼠的胃蛋白酶原分泌没有显著影响。100毫摩尔/升盐酸、100毫摩尔/升氯化钠和150毫摩尔/升蔗糖溶液均对胃蛋白酶原分泌产生类似的刺激作用。这些结果不支持以下观点：在生理条件下，胃黏膜含有对氢离子敏感的受体来调节胃蛋白酶原的分泌。
