Ghosh S, Echols H
Proc Natl Acad Sci U S A. 1972 Dec;69(12):3660-4. doi: 10.1073/pnas.69.12.3660.
D factor is protein that stimulates DNA transcription in vitro by RNA polymerase. For DNA from bacteriophage lambda, we present evidence that D protein interacts with DNA to increase the frequency and improve the specificity of initiation by RNA polymerase.
D因子是一种在体外能刺激RNA聚合酶进行DNA转录的蛋白质。对于来自λ噬菌体的DNA,我们提供的证据表明,D蛋白与DNA相互作用,可提高RNA聚合酶起始转录的频率并增强其特异性。