Aqueous central cavity in aspartate transcarbamylase from Escherichia coli.
作者信息
Evans D R, Warren S G, Edwards B F, McMurray C H, Bethge P H, Wiley D C, Lipscomb W N
出版信息
Science. 1973 Feb 16;179(4074):683-5. doi: 10.1126/science.179.4074.683.
PMID:4567940
Abstract
A three-dimensional x-ray diffraction study of aspartate transcarbamylase to 5.5-angstrom resolution, with the aid of four isomorphous heavy atom derivatives, indicates the presence of a central aqueous cavity approximating an oblate spheroid about 25 by 50 by 50 angstroms in dimension, within a molecule about 90 by 110 by 110 angstroms in largest dimensions.
摘要
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