来自大肠杆菌的天冬氨酸转氨甲酰酶中的水性中央腔。
Aqueous central cavity in aspartate transcarbamylase from Escherichia coli.
作者信息
Evans D R, Warren S G, Edwards B F, McMurray C H, Bethge P H, Wiley D C, Lipscomb W N
出版信息
Science. 1973 Feb 16;179(4074):683-5. doi: 10.1126/science.179.4074.683.
PMID:4567940
Abstract
A three-dimensional x-ray diffraction study of aspartate transcarbamylase to 5.5-angstrom resolution, with the aid of four isomorphous heavy atom derivatives, indicates the presence of a central aqueous cavity approximating an oblate spheroid about 25 by 50 by 50 angstroms in dimension, within a molecule about 90 by 110 by 110 angstroms in largest dimensions.
摘要
借助四种同晶型重原子衍生物，对天冬氨酸转氨甲酰酶进行了分辨率达5.5埃的三维X射线衍射研究，结果表明在最大尺寸约为90×110×110埃的分子内，存在一个近似扁球体的中央水腔，其尺寸约为25×50×50埃。
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