Naujoks H, Köpf F, Leber I
Geburtshilfe Frauenheilkd. 1979 May;39(5):372-7.
Before conization in 108 patients with cervical intraepithelial neoplasia (CIN) colposcopic findings and the results of triple cervical smears (anterior and posterior cervical lip and endocervical canal) have been evaluated and compared with the microscopic findings, limiting the comparison to the separately investigated anterior and posterior cervical lips. Colposcopically and cytologically suspicious findings agreed with the microscopic findings of CIN in 48.3% (anterior lip) resp. 41.7% (posterior lip). Cytologically suspicious findings alone have been determined in 80.5% resp. 84.8%; colposcopically suspicious findings were found in 55.2% resp. 48.1%. The main causes of false negative smears may have been failures of sampling, of false negative colposcopical findings a wrong estimation of an atypical transformation zone. A combined application of colposcopy and triple cervical smear technique in patients with abnormal smears is strongly recommended. This may improve the results of localizing a lesion of CIN.
对108例宫颈上皮内瘤变(CIN)患者在进行锥切术前,已对阴道镜检查结果和宫颈三联涂片(宫颈前后唇及宫颈管)结果进行了评估,并与显微镜检查结果进行了比较,且将比较局限于分别检查的宫颈前后唇。阴道镜检查和细胞学检查的可疑结果分别与CIN显微镜检查结果相符的比例为48.3%(前唇)和41.7%(后唇)。单独细胞学检查可疑结果分别为80.5%和84.8%;阴道镜检查可疑结果分别为55.2%和48.1%。涂片假阴性的主要原因可能是取样失败,而阴道镜检查假阴性的原因可能是对非典型转化区的错误判断。强烈建议对涂片异常的患者联合应用阴道镜检查和宫颈三联涂片技术。这可能会改善CIN病变定位的结果。