Daniel A
Hum Genet. 1979 Apr 17;48(1):85-92. doi: 10.1007/BF00273279.
Six human dicentric translocations involving the presence of a suppressed centromere were studied: one case of t dic(9;22), one of t dic(13;18), one of t dic(14;15), and three of t dic(13;14). All exhibited chromatid separation at an acrocentric centromere and were demonstrated to have two regions of centromeric constitutive heterochromatin. The four that were available for retrospective study showed a single Cd band, with absence of the Cd band at the suppressed centromere.
研究了6例涉及抑制着丝粒存在的人类双着丝粒易位:1例t dic(9;22)、1例t dic(13;18)、1例t dic(14;15)和3例t dic(13;14)。所有病例在近端着丝粒处均表现出染色单体分离,并被证明有两个着丝粒组成型异染色质区域。可供回顾性研究的4例显示有一条Cd带,而在抑制着丝粒处没有Cd带。