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capR(lon)和capT基因对乳糖操纵子的转录调控。

Transcriptional control of the calactose operon by the capR (lon) and capT genes.

作者信息

Buchanan C E, Hua S S, Avni H, Markovitz A

出版信息

J Bacteriol. 1973 May;114(2):891-3. doi: 10.1128/jb.114.2.891-893.1973.

DOI:10.1128/jb.114.2.891-893.1973
PMID:4574707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC251856/
Abstract

Mutations in capR or capT cause derepression of the enzymes of the gal operon. The gal-specific messenger ribonucleic acid is directly proportional to the gal enzyme levels in wild type, capR, and capT strains. These results indicate that capR and capT control the gal operon at the transcriptional level.

摘要

capR或capT基因发生突变会导致半乳糖操纵子的酶去阻遏。在野生型、capR和capT菌株中,半乳糖特异性信使核糖核酸与半乳糖酶水平成正比。这些结果表明,capR和capT在转录水平上控制半乳糖操纵子。

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1
Transcriptional control of the calactose operon by the capR (lon) and capT genes.capR(lon)和capT基因对乳糖操纵子的转录调控。
J Bacteriol. 1973 May;114(2):891-3. doi: 10.1128/jb.114.2.891-893.1973.
2
Multiple regulator gene control of the galactose operon in Escherichia coli K-12.大肠杆菌K-12中半乳糖操纵子的多调节基因控制
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4
Regulation of the gal operon of Escherichia coli by the capR gene.大肠杆菌capR基因对gal操纵子的调控
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Galactose-specific messenger ribonucleic acid contents in Escherichia coli: effect of inducer, gene dosage and galactose genotype.大肠杆菌中半乳糖特异性信使核糖核酸的含量:诱导物、基因剂量和半乳糖基因型的影响。
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6
Multiple regulation of the galactose operon-genetic evidence for a distinct site in the galactose operon that responds to capR gene regulation in Escherichia coli K-12.半乳糖操纵子的多重调控——大肠杆菌K-12中半乳糖操纵子内一个对capR基因调控有响应的独特位点的遗传学证据
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Regulation of gal messenger ribonucleic acid synthesis in Escherichia coli by 3',5'-cyclic adenosine monophosphate.3',5'-环磷酸腺苷对大肠杆菌中半乳糖信使核糖核酸合成的调控
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引用本文的文献

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2
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J Bacteriol. 1982 Nov;152(2):919-23. doi: 10.1128/jb.152.2.919-923.1982.
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J Bacteriol. 1984 Jul;159(1):283-7. doi: 10.1128/jb.159.1.283-287.1984.
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Proc Natl Acad Sci U S A. 1981 Apr;78(4):2043-7. doi: 10.1073/pnas.78.4.2043.
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6
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本文引用的文献

1
HEREDITARY DEFECTS IN GALACTOSE METABOLISM IN ESCHERICHIA COLI MUTANTS, I. DETERMINATION OF ENZYME ACTIVITIES.大肠杆菌突变体中半乳糖代谢的遗传性缺陷,I. 酶活性的测定
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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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[REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF THE ENZYMES OF GALACTOSE METABOLISM IN ESCHERICHIA COLI K 12. II. THE GENETIC DETERMINISM OF THE REGULATION].[大肠杆菌K12中半乳糖代谢酶生物合成的调控机制。II. 调控的遗传决定因素]
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Synthesis and turnover of phage messenger RNA in E. coli infected with bacteriophage T4 in the presence of chloromycetin.在氯霉素存在的情况下,被噬菌体T4感染的大肠杆菌中噬菌体信使RNA的合成与周转
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A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane.一种用于检测固定在膜上的DNA与RNA杂交体的定量分析方法。
J Mol Biol. 1965 Jul;12(3):829-42. doi: 10.1016/s0022-2836(65)80331-x.
6
Isolation of the gal repressor.半乳糖阻遏物的分离
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1891-5. doi: 10.1073/pnas.68.8.1891.
7
Orientation of transcription for the galactose operon as determined by hybridization of gal mRNA with the separated DNA strands of coliphages lambda-dg.通过半乳糖信使核糖核酸(gal mRNA)与大肠杆菌噬菌体λ-dg的单链DNA杂交确定半乳糖操纵子的转录方向。
J Mol Biol. 1968 Jul 14;35(1):207-13. doi: 10.1016/s0022-2836(68)80048-8.
8
The galactose operon of E. coli K-12. II. A deletion analysis of operon structure and polarity.大肠杆菌K-12的半乳糖操纵子。II. 操纵子结构与极性的缺失分析。
Genetics. 1969 Jun;62(2):249-64. doi: 10.1093/genetics/62.2.249.
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Negative control of the galactose operon in E. coli.
Mol Gen Genet. 1968;102(1):79-88. doi: 10.1007/BF00341872.
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Isolation of plaque-forming, galactose-transducing strains of phage lambda.λ噬菌体形成噬菌斑、转导半乳糖菌株的分离
Genetics. 1972 Jun;71(2):189-206. doi: 10.1093/genetics/71.2.189.