Kaplan M S, Solli N J
J Allergy Clin Immunol. 1979 Aug;64(2):122-6. doi: 10.1016/0091-6749(79)90045-9.
Over a 3-yr period, 18 children , ages 10 mo to 5 yr, were discovered to have IgE to cow's-milk protein (CMP). They were compared with 18 age-matched patients for having been primarily breast fed during the first 6 mo of life. All were new allergy clinic asthmatic patients with a strong family history of atopy and evidence of IgE to multiple allergens. Analysis of the data on this allergic population revealed that both a history of breast feeding and of milk-induced immediate reaction in patients with CMP-specific IgE was significantly higher (p is less than 0.03) than in those patients without IgE to CMP. Inadvertent sensitization to food antigens can occur in some atopic breast-fed infants.
在3年的时间里，发现18名年龄在10个月至5岁的儿童对牛奶蛋白（CMP）有IgE。将他们与18名年龄匹配的患者进行比较，比较内容为在生命的前6个月是否主要进行母乳喂养。所有患者均为新的过敏诊所哮喘患者，有强烈的特应性家族病史，且有对多种过敏原的IgE证据。对该过敏人群的数据分析显示，有母乳喂养史以及有CMP特异性IgE的患者出现牛奶诱导的速发型反应的比例显著高于无CMP IgE的患者（p<0.03）。一些特应性母乳喂养婴儿可能会意外对食物抗原致敏。
