首次已知接触某种食物时出现的速发型食物过敏反应。
Immediate food hypersensitivity reactions on the first known exposure to the food.
作者信息
van Asperen P P, Kemp A S, Mellis C M
出版信息
Arch Dis Child. 1983 Apr;58(4):253-6. doi: 10.1136/adc.58.4.253.
Abstract
We report 8 infants with immediate hypersensitivity reactions to foods (milk, egg, or peanut), occurring at the first-known exposure. Each developed symptoms within the first hour, but these generally settled within 2 hours. Sensitisation to the food concerned was demonstrated by positive immediate allergen skin prick tests in every case. Symptoms experienced included irritability, erythematous rash, urticaria, angio-oedema, vomiting, rhinorrhoea, and cough. Five infants were being followed prospectively and 4 were clinically tolerant of the food by age 16 months. The most likely route of sensitisation was via breast milk. None of the infants experienced similar reactions while being breast fed, suggesting that the reaction was dose dependent. As 5 out of a group of 80 infants being followed prospectively developed an immediate reaction at their first known exposure to a food, this appeared to be a not uncommon presentation of food hypersensitivity in infancy.
摘要
我们报告了8名首次接触食物（牛奶、鸡蛋或花生）后立即出现过敏反应的婴儿。每名婴儿在1小时内均出现症状，但这些症状通常在2小时内缓解。通过即时过敏原皮肤点刺试验，每例均显示对相关食物过敏。所经历的症状包括烦躁、红斑疹、荨麻疹、血管性水肿、呕吐、鼻溢和咳嗽。5名婴儿接受了前瞻性随访，4名婴儿在16个月大时对该食物具有临床耐受性。最可能的致敏途径是通过母乳。母乳喂养期间，没有婴儿出现类似反应，提示该反应与剂量有关。在80名接受前瞻性随访的婴儿中，有5名在首次接触某种食物时立即出现反应，这似乎是婴儿期食物过敏的一种常见表现。
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