Collin J, Tweedle D E, Venables C W, Constable F L, Johnston I D
Br Med J. 1973 Nov 24;4(5890):456-8. doi: 10.1136/bmj.4.5890.456.
The Millipore filter unit has been advocated as a means of reducing the chance of bacteria entering the circulation during intravenous infusion. In a prospective study no significant reduction was obtained in the incidence of thrombophlebitis or in the bacterial contamination of cannulae. The unit was inconvenient to use and in-vitro and in-vivo studies showed reduced flow rates and frequent episodes of filter blockage. Its use was further restricted by the fact that blood and fat emulsions would not pass through it.
密理博过滤装置一直被提倡作为一种减少静脉输液期间细菌进入循环系统几率的手段。在一项前瞻性研究中,血栓性静脉炎的发生率或套管的细菌污染情况均未得到显著降低。该装置使用不便,体外和体内研究表明其流速降低且经常出现过滤器堵塞的情况。血液和脂肪乳剂无法通过该装置这一事实进一步限制了其使用。